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George Clooney's heartfelt message after sad loss

George Clooney has shared a heartfelt message to his Ocean's Eleven co-star, Scott L. Schwartz, who sadly passed away aged 65. "I'm sorry to hear that Scott is gone," he told Variety. "We did three films together and I've never been so gently punched," Clooney continued. "He was a gentle soul and he will be dearly missed." Schwartz, who stood at six feet and 10 inches (approx. 208.3cm) tall, played Bruiser in the Ocean's Eleven trilogy, alongside Clooney, Matt Damon, Brad Pitt, Julia Roberts and more Hollywood stars. Clooney's character in the film, Danny Ocean, hires Bruiser to pretend to beat him up during the group's casino heist. Schwartz's wife Misty confirmed he died on November 26 at his Covington, Los Angeles home, according to People. His cause of death is understood to be congestive heart failure. Misty said while he was known for the Ocean's film, she was "most proud of his charity work", which saw him be honoured with the Glass Slipper Award from children's healthcare foundation CHOC. "Most people associate Scott with the movies, but those who know him personally associated him with being a jolly person, so full of life, a strong loving person, foodie and travel aficionado," his wife told People. "Life won't be the same without him." Schwartz is survived by his wife, Misty, and children Angela and Adam. Image: SplashNews.com/ Shutterstock Editorial

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3 key differences between an ocean and river cruise

People often have a personal preference when it comes to ocean cruises or river cruises, so if you’re not sure what to go for, it’s best to know how they really differ before booking your next trip. Here are the three key differences between an ocean and river cruise. 1. Cost River cruises are initially more expensive, and travellers can expect the price to be from $200-500 per person per night. Ocean ships can cost less than $100 per night if you get a good deal. However, once onboard your ocean cruise there will be a likelihood that you splurge on extra costs such as drinks, tours and souvenirs. 2. Inclusions Only the most upmarket ocean cruises are all-inclusive but on an ocean cruise if you want mealtime alcohol, Wi-Fi and other extras, you will be expected to pay up. All these extras are included in river-cruise fares and sometimes airport transfers are included too. River cruises require you to pay a heftier sum upon booking but if you are going on an ocean cruise, be sure to keep track of your spending. 3. Ship amenities On river cruises, expect your onboard entertainment to be a massage room, fitness room or hot tub as most of the focus is on the destination. However, ocean cruises are lined with Broadway-styled shows, casinos, kids’ clubs, water parks, spas and various pools. If you prefer a quiet, intimate setting then river cruises would suit your desires but if you want a wide-range of entertainment, ocean cruises are for you. Image credits: Shutterstock

Cruising

How can we improve public health communication for the next pandemic? Tackling distrust and misinformation is key

<a href="https://theconversation.com/profiles/shauna-hurley-203140">Shauna Hurley</a>, <a href="https://theconversation.com/institutions/monash-university-1065">Monash University</a> and <a href="https://theconversation.com/profiles/rebecca-ryan-1522824">Rebecca Ryan</a>, <a href="https://theconversation.com/institutions/la-trobe-university-842">La Trobe University</a> There’s a common thread linking our <a href="https://www.visualcapitalist.com/history-of-pandemics-deadliest/">experience of pandemics</a> over the past 700 years. From the black death in the 14th century to COVID in the 21st, public health authorities have put emergency measures such as isolation and quarantine in place to stop infectious diseases spreading. As we know from COVID, these measures upend lives in an effort to save them. In both the <a href="https://www.thinkglobalhealth.org/article/pandemic-protests-when-unrest-and-instability-go-viral">recent</a> and <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3559034/">distant past</a> they’ve also given rise to collective unrest, confusion and resistance. So after all this time, what do we know about the role public health communication plays in helping people understand and adhere to protective measures in a crisis? And more importantly, in an age of misinformation and distrust, how can we improve public health messaging for any future pandemics? Last year, we published a <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD015144/full">Cochrane review</a> exploring the global evidence on public health communication during COVID and other infectious disease outbreaks including SARS, MERS, influenza and Ebola. Here’s a snapshot of what we found. <h2>The importance of public trust</h2> A key theme emerging in analysis of the COVID pandemic globally is public trust – or lack thereof – in governments, public institutions and science. Mounting evidence suggests <a href="https://www.washingtonpost.com/world/2022/02/01/trust-lancet-covid-study/">levels of trust in government</a> were <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00172-6/fulltext">directly proportional</a> to fewer COVID infections and higher vaccination rates across the world. It was a crucial factor in people’s willingness to follow public health directives, and is now a key focus for future pandemic preparedness. Here in Australia, public trust in governments and health authorities steadily eroded over time. Initial information from governments and health authorities about the unfolding COVID crisis, personal risk and mandated protective measures was generally clear and consistent across the country. The establishment of the <a href="https://www.aph.gov.au/About_Parliament/Parliamentary_Departments/Parliamentary_Library/pubs/rp/rp1920/Quick_Guides/AustralianCovid-19ResponseManagement#_Toc38973752">National Cabinet</a> in 2020 signalled a commitment from state, territory and federal governments to consensus-based policy and public health messaging. During this early phase of relative unity, <a href="https://theconversation.com/inflation-covid-inequality-new-report-shows-australias-social-cohesion-is-at-crossroads-195198">Australians reported</a> higher levels of belonging and trust in government. But as the pandemic wore on, public trust and confidence fell on the back of conflicting state-federal pandemic strategies, blame games and the <a href="https://theconversation.com/we-lost-the-plot-on-covid-messaging-now-governments-will-have-to-be-bold-to-get-us-back-on-track-186732">confusing fragmentation</a> of public health messaging. The divergence between <a href="https://www.theaustralian.com.au/nation/tale-of-two-cities-gripped-by-covid-fear-outbreak/news-story/cf1b922610aeb0b0ee9b0b53486bf640">lockdown policies and public health messaging</a> adopted by <a href="https://www.theage.com.au/national/victoria/a-tale-of-two-cities-that-doesn-t-seem-fair-20211012-p58z79.html">Victoria and New South Wales</a> is one example, but there are plenty of others. When state, territory and federal governments have conflicting policies on protective measures, people are easily confused, lose trust and become harder to engage with or persuade. Many tune out from partisan politics. Adherence to mandated public health measures falls. Our research found clarity and consistency of information were key features of effective public health communication throughout the COVID pandemic. We also found public health communication is most effective when authorities work in partnership with different target audiences. In Victoria, the case brought against the state government for the <a href="https://www.abc.net.au/news/2023-07-24/melbourne-public-housing-tower-covid-lockdown-compensation/102640898">snap public housing tower lockdowns</a> is a cautionary tale underscoring how essential considered, tailored and two-way communication is with diverse communities. <h2>Countering misinformation</h2> Misinformation is <a href="https://reutersinstitute.politics.ox.ac.uk/hydroxychloroquine-australia-cautionary-tale-journalists-and-scientists">not a new problem</a>, but has been supercharged by the advent of <a href="https://theconversation.com/health-misinformation-is-rampant-on-social-media-heres-what-it-does-why-it-spreads-and-what-people-can-do-about-it-217059">social media</a>. The much-touted “miracle” drug <a href="https://www.vox.com/future-perfect/22663127/ivermectin-covid-treatments-vaccines-evidence">ivermectin</a> typifies the extraordinary traction unproven treatments gained locally and globally. Ivermectin is an anti-parasitic drug, lacking evidence for viruses like COVID. Australia’s drug regulator was forced to <a href="https://www.theguardian.com/australia-news/2021/sep/10/australian-drug-regulator-bans-ivermectin-as-covid-treatment-after-sharp-rise-in-prescriptions">ban ivermectin presciptions</a> for anything other than its intended use after a <a href="https://www.theguardian.com/world/2021/aug/30/australian-imports-of-ivermectin-increase-10-fold-prompting-warning-from-tga">sharp increase</a> in people seeking the drug sparked national shortages. Hospitals also reported patients <a href="https://www.theguardian.com/australia-news/2021/sep/02/sydney-covid-patient-in-westmead-hospital-after-overdosing-on-ivermectin-and-other-online-cures">overdosing on ivermectin</a> and cocktails of COVID “cures” promoted online. The <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01585-9/fulltext">Lancet Commission</a> on lessons from the COVID pandemic has called for a coordinated international response to countering misinformation. As part of this, it has called for more accessible, accurate information and investment in scientific literacy to protect against misinformation, including that shared across social media platforms. The World Health Organization is developing resources and recommendations for health authorities to address this “<a href="https://www.who.int/health-topics/infodemic#tab=tab_1">infodemic</a>”. National efforts to directly tackle misinformation are vital, in combination with concerted efforts to raise health literacy. The Australian Medical Association has <a href="https://www.ama.com.au/media/action-needed-tackle-health-misinformation-internet-social-media">called on the federal government</a> to invest in long-term online advertising to counter health misinformation and boost health literacy. People of all ages need to be equipped to think critically about who and where their health information comes from. With the rise of AI, this is an increasingly urgent priority. <h2>Looking ahead</h2> Australian health ministers recently <a href="https://www.cdc.gov.au/newsroom/news-and-articles/australian-health-ministers-reaffirm-commitment-australian-cdc">reaffirmed their commitment</a> to the new Australian Centre for Disease Control (CDC). From a science communications perspective, the Australian CDC could provide an independent voice of evidence and consensus-based information. This is exactly what’s needed during a pandemic. But full details about the CDC’s funding and remit have been the subject of <a href="https://www.croakey.org/federal-budget-must-deliver-on-climate-health-and-the-centre-for-disease-control-sector-leaders-warn/">some conjecture</a>. Many of our <a href="https://www.cochraneaustralia.org/articles/covidandcommunications">key findings</a> on effective public health communication during COVID are not new or surprising. They reinforce what we know works from previous disease outbreaks across different places and points in time: tailored, timely, clear, consistent and accurate information. The rapid rise, reach and influence of misinformation and distrust in public authorities bring a new level of complexity to this picture. Countering both must become a central focus of all public health crisis communication, now and in the future. This article is part of a <a href="https://theconversation.com/au/topics/the-next-pandemic-160343">series on the next pandemic</a>.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/226718/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/shauna-hurley-203140">Shauna Hurley</a>, PhD candidate, School of Public Health, <a href="https://theconversation.com/institutions/monash-university-1065">Monash University</a> and <a href="https://theconversation.com/profiles/rebecca-ryan-1522824">Rebecca Ryan</a>, Senior Research Fellow, Health Practice and Management; Head, Centre for Health Communication and Participation, <a href="https://theconversation.com/institutions/la-trobe-university-842">La Trobe University</a> Image credits: Shutterstock This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/how-can-we-improve-public-health-communication-for-the-next-pandemic-tackling-distrust-and-misinformation-is-key-226718">original article</a>.

Technology

Jon Bon Jovi praised for talking woman off bridge

Content warning: This article contains mentions of suicide. Jon Bon Jovi has helped to persuade a woman standing on the ledge of a bridge in Nashville to come back over the railing, likely saving her life. The Metro Nashville Police Department revealed that the encounter happened on Tuesday night on the Seigenthaler Pedestrian Bridge. The rock star was filming a music video for his song The People's House on the bridge, when he spotted the woman on the ledge, according to the New York Post. Surveillance footage shared by the city's police department on X showed the singer approaching the woman, alongside another bystander and not long after they helped pull her over the railing and away from danger. After the woman was safe, she and Bon Jovi hugged. "A shout out to @jonbonjovi & his team for helping a woman on the Seigenthaler Ped Bridge Tue night," the Metro Nashville Police Department shared on X. <blockquote class="twitter-tweet"> A shout out to <a href="https://twitter.com/jonbonjovi?ref_src=twsrc%5Etfw">@jonbonjovi</a> & his team for helping a woman on the Seigenthaler Ped Bridge Tue night. Bon Jovi helped persuade her to come off the ledge over the Cumberland River to safety. "It takes all of us to help keep each other safe,"--Chief John Drake <a href="https://t.co/1YejKJ2WgM">https://t.co/1YejKJ2WgM</a> — Metro Nashville PD (@MNPDNashville) <a href="https://twitter.com/MNPDNashville/status/1833970989354348832?ref_src=twsrc%5Etfw">September 11, 2024</a></blockquote> "Bon Jovi helped persuade her to come off the ledge over the Cumberland River to safety. 'It takes all of us to help keep each other safe,'--Chief John Drake." The bridge was completely open to the public at the time Bon Jovi was filming his music video. While the singer told The Post that he won't be making any public comments out of respect for the person and their privacy, another source told them that Bon Jovi did what any person who found themselves in that situation would've done. Images: Metropolitan Nashville Police Department

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Body found in search for wife of former rugby star

A body has been found in the search for Jenny Hastings, the wife of the former Scotland rugby star Scott Hastings. Jenny, 60, went missing at Wardie Bay, a wild swimming spot near Edinburgh, on Tuesday. A massive search involving police, ambulance and coastguard crews was launched in the Firth of Forth, according to The Sun. Despite their efforts, the search was stood down on Tuesday night. On Saturday afternoon, police said a woman's body was found in the Hound Point area of South Queensferry, near Edinburgh. Formal identification has yet to take place, but police said that: “The family of missing woman Jenny Hastings has been informed.” They also said "there did not appear to be any suspicious circumstances and a report will be submitted to the Procurator Fiscal". Police were treating her disappearance as a “high-risk missing persons case,” as Jenny struggles with her mental health. Her family previously issued a statement amid fears she was dead. “It appears that she wished to end her suffering in what was a regular and healing place for her," they said. “She loved the water but unfortunately her mind was not in a place of safety. “The Hastings family are absolutely heartbroken. We miss our Jenny. “She leaves a gaping hole in all our hearts and hope that she is returned to us safely so that we can celebrate her remarkable life.” Scottish Rugby also shared a statement on social media yesterday, sending their love and support to the Hastings family. “Scottish Rugby sends its love and support to Scott Hastings, Scotland cap 848, after his wife Jenny was reported missing whilst swimming earlier this week. “Our thoughts are with their children, and the wider Hastings family, at this heartbreaking time.” Jenny had been open about her struggles with mental health. In March 2017, she disappeared from the couple's Edinburgh home for 36 hours and walked to the Pentland Hills while she was suffering from depression. The couple both became ambassadors for charity Support in Mind Scotland and devoted work to helping others with their own mental health by staying active. They helped launch the 100 Streets challenge, encouraging people to get out and exercise with friends. Images: news.com.au

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Major breakthrough holds the key to diagnosing Alzheimer's

A new study has found that a simple blood test could be key to diagnosing Alzheimer's more quickly and more accurately. The research, published on the Journal of the American Medical Association, was conducted by a team of scientists at Sweden’s Lund University, was based off 1213 patients there with the condition. They found that a blood test could correctly identify whether patients with memory problems had Alzheimer’s 90 per cent of the time – making it “significantly” more accurate than cognitive tests and CAT scans in diagnosing the condition. The test itself measures tau protein 217, which if there is an abnormal build up of both in and around brain cells, may be the cause of the disease. “Increases in p tau-217 concentrations in the blood are quite profound in Alzheimer’s disease,” study co-author, Lund University associate professor and senior consultant neurologist, Dr Sebastian Palmqvist, told CNN. “At the dementia stage of the disease, levels are more than eight times higher compared with elderly (people) without Alzheimer’s.” As part of the study, the p tau-217 test was combined with one testing for another blood biomarker for Alzheimer’s called the amyloid 42/40 ratio. Other doctors have shared their thoughts on the research findings, with Chief science officer of America’s Alzheimer’s Association, Dr Maria Carrillo, telling CNN that doctors would “love to have a blood test that can be used in a primary care physician’s office, functioning like a cholesterol test but for Alzheimer’s”. “The p tau-217 blood test is turning out to be the most specific for Alzheimer’s and the one with the most validity. It seems to be the frontrunner,” she added. Blood tests like this could “change the game in the speed in which we can conduct Alzheimer’s trials and get to the next new medication”. Dr Jason Karlawish, the co-director at the University of Pennsylvania’s Penn Memory Centre, said of the research: “Not too long ago measuring pathology in the brain of a living human was considered just impossible.” “This study adds to the revolution that has occurred in our ability to measure what’s going on in the brain of living humans.” Image: Shutterstock

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Hospice nurse reveals the key to a peaceful death

Hospice nurse Julie McFadden has shared her best advice for ensuring a peaceful death, after learning from her patients in their final moments. The healthcare professional, who is known for her YouTube channel where she shares information about death to break the taboo of conversations around dying, shared a video about what you can do in life to ensure a peaceful passing. In the recent clip, she shared what you can do in order to have a peaceful death, and she says it comes down to preparedness and acceptance. "That's one of the biggest things I see," she explained. "People who plan for death will tend to have a more peaceful death than those who do not plan for death." "A prepared death versus a non-prepared death - that's the one thing that I've seen in all of my patients," she explained. Julie said she noticed the patients that were "willing to talk about the hard stuff" had a more peaceful death. <iframe title="YouTube video player" src="https://www.youtube.com/embed/qoFvKkfIo00?si=Ba5BnxuaKsBVaGAe" width="560" height="315" frameborder="0" allowfullscreen="allowfullscreen"></iframe> "[That means] willing to ask the questions about, 'how long do you think I have? What can I expect? What should I do before I die to make this easier for my family?'" she listed. Julie went on to share a story of when a patient of hers died peacefully surrounded by his family, explaining that the patient was in hospice and had started to decline around 20 minutes after she arrived. "He started having weird changes in breathing, so this was a sudden decline and it looked like he may suddenly die," she recalled, adding the abrupt change was "uncommon actually" in hospice care. "What I noticed was because this family - and him - were so prepared, instead of the family [being] chaotic and reacting in an emotional way - which is very normal - they flipped along right with him," she explained. "[They laid] in bed with him. They understood immediately what was happening. They didn't panic," she shared. Julie said the man was surrounded by his loving family and it was an overwhelmingly emotional experience. "It makes me cry every time I think about it - that vision of them all being able to understand what was happening, even though it was a change they didn't want," she explained. "By the end of that visit he died, so he went from kind of looking okay to dying which is hard - but that family made it a beautiful moment," she said. Image credits: YouTube

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"Family unity is key": Sarah Ferguson gives cancer update

Sarah Ferguson has shared an update on her cancer journey during her appearance at the Cannes Film Festival. The Duchess of York was diagnosed with <a href="https://www.oversixty.com.au/health/caring/fergie-reveals-second-cancer-diagnosis" target="_blank" rel="noopener">skin cancer</a> in January, not long after getting a mastectomy for her breast cancer, which she was diagnosed with in June 2023. When asked about her health, the royal told People: "This evening I am doing very well. I think that we've managed to get cancer in the right place rather than cancer ruling me. I've put cancer in the corner." Speaking on the amfAR Gala red carpet, the 64-year-old added that it was important to be aware and get checked for both breast cancer and melanoma. “I think you always have to be aware. I think it’s great to get checked for breast cancer [and] melanoma. I think you just have to be very candid about it," she told the publication. “I think a lot of people get very frightened to talk about these things. I’m very happy with my mastectomy and my breasts and just to talk about it.” Her diagnosis coincided with both her brother-in-law King Charles, and Princess Catherine's cancer diagnoses, although both of them have not disclosed what types of cancer they have. She praised the royal family for their "unity" during these difficult times and how she has been able to offer support to Charles and Catherine. "I think family unity is key… I think the key to life is that we all support each other," she said. "And also forgiveness is a great thing. I think forgiveness of yourself, and forgiveness of others." Earlier this month, the duchess' eldest daughter Princess Beatrice spoke about her mother's health in her debut TV interview on This Morning. "She’s such a phenomenal icon. As a mum she’s been amazing," she said, adding that despite going through so much in the last year, she felt inspired by her mum's resilience and sense of purpose. “She’s doing really well. She had a bumpy health scare last year but she’s all clear now. But I think at 64, she’s thriving. She’s been through so much, but now she’s coming into her own. “We are just reminded when any parent or individual has a health scenario, you really need to get the checks you need as early as you possibly can.” Image: DGP/imageSPACE/ Shutterstock editorial

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People in the world’s ‘blue zones’ live longer – their diet could hold the key to why

<a href="https://theconversation.com/profiles/justin-roberts-1176632">Justin Roberts</a>, <a href="https://theconversation.com/institutions/anglia-ruskin-university-1887">Anglia Ruskin University</a>; <a href="https://theconversation.com/profiles/joseph-lillis-1505087">Joseph Lillis</a>, <a href="https://theconversation.com/institutions/anglia-ruskin-university-1887">Anglia Ruskin University</a>, and <a href="https://theconversation.com/profiles/mark-cortnage-438941">Mark Cortnage</a>, <a href="https://theconversation.com/institutions/anglia-ruskin-university-1887">Anglia Ruskin University</a> Ageing is an inevitable part of life, which may explain our <a href="https://time.com/4672969/why-do-people-want-to-live-so-long/">strong fascination</a> with the <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726954">quest for longevity</a>. The allure of <a href="https://pubmed.ncbi.nlm.nih.gov/26566891/">eternal youth</a> drives a <a href="https://www.alliedmarketresearch.com/longevity-and-anti-senescence-therapy-market-A14010">multi-billion pound industry</a> ranging from anti-ageing products, supplements and <a href="https://www.everydayhealth.com/diet-nutrition/longevity-diet">diets</a> for those hoping to extend their lifespan. f you look back to the turn of the 20th century, average life expectancy in the UK was around 46 years. Today, it’s closer to <a href="https://population.un.org/wpp/">82 years</a>. We are in fact <a href="https://pubmed.ncbi.nlm.nih.gov/27706136/">living longer than ever before</a>, possibly due to medical advancements and improved <a href="https://www.health.org.uk/publications/reports/mortality-and-life-expectancy-trends-in-the-uk">living and working conditions</a>. But living longer has also come at a price. We’re now seeing higher rates of <a href="https://www.who.int/data/gho/data/themes/mortality-and-global-health-estimates/ghe-leading-causes-of-death">chronic and degenerative diseases</a> – with heart disease consistently topping the list. So while we’re fascinated by what may help us live longer, maybe we should be more interested in being healthier for longer. Improving our “<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632858/">healthy life expectancy</a>” remains a global challenge. Interestingly, certain locations around the world have been discovered where there are a high proportion of centenarians who display remarkable physical and mental health. The <a href="https://pubmed.ncbi.nlm.nih.gov/15489066/">AKEA study of Sardinia, Italy</a>, as example, identified a “blue zone” (named because it was marked with blue pen), where there was a higher number of locals living in the central-eastern mountainous areas who had reached their 100th birthday compared with the wider Sardinian community. This longevity hotspot has since been expanded, and now includes several other areas around the world which also have greater numbers of longer-living, healthy people. Alongside Sardinia, these blue zones are now <a href="https://www.netflix.com/gb/title/81214929">popularly recognised</a> as: Ikaria, Greece; Okinawa, Japan; Nicoya, Costa Rica; and Loma Linda, California. Other than their long lifespans, people living in these zones also appear to share certain other commonalities, which centre around being <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874460">part of a community</a>, having a <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224996/">life purpose</a>, eating <a href="https://pubmed.ncbi.nlm.nih.gov/33514872/">nutritious, healthy foods</a>, keeping <a href="https://www.nature.com/articles/s41398-021-01735-7">stress levels</a> low and undertaking purposeful daily <a href="https://pubmed.ncbi.nlm.nih.gov/30202288/">exercise or physical tasks</a>. Their longevity could also relate to their <a href="https://pubmed.ncbi.nlm.nih.gov/9010380/">environment</a>, being mostly rural (or less polluted), or because of <a href="https://pubmed.ncbi.nlm.nih.gov/22253498/">specific longevity genes</a>. However, studies indicate genetics may only account for <a href="https://pubmed.ncbi.nlm.nih.gov/8786073">around 20-25% of longevity</a> – meaning a person’s lifespan is a complex interaction between lifestyle and genetic factors, which contribute to a long and healthy life. <h2>Is the secret in our diet?</h2> When it comes to diet, each blue zone has its own approach – so one specific food or nutrient does not explain the remarkable longevity observed. But interestingly, a diet rich in <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662288">plant foods</a> (such as locally-grown vegetables, fruits and legumes) does appear to be reasonably consistent across these zones. For instance, the Seventh-day Adventists of Loma Linda are <a href="https://pubmed.ncbi.nlm.nih.gov/10641813/">predominately vegetarian</a>. For centenarians in Okinawa, <a href="https://pubmed.ncbi.nlm.nih.gov/20234038/">high intakes of flavonoids</a> (a chemical compound typically found in plants) from purple sweet potatoes, soy and vegetables, have been linked with <a href="https://pubmed.ncbi.nlm.nih.gov/11710359/">better cardiovascular health</a> – including lower cholesterol levels and lower incidences of stroke and heart disease. In Nicoya, consumption of locally produced rice and beans has been associated with <a href="https://pubmed.ncbi.nlm.nih.gov/34444746/">longer telomere length</a>. Telomeres are the structural part at the end of our chromosomes which protect our genetic material. Our telomeres get shorter each time a cell divides – so get progressively shorter as we age. Certain <a href="https://pubmed.ncbi.nlm.nih.gov/21102320/">lifestyle factors</a> (such as smoking and poor diet) can also shorten telomere length. It’s thought that telomere length acts as a <a href="https://pubmed.ncbi.nlm.nih.gov/31728493/">biomarker of ageing</a> – so having longer telomeres could, in part, be linked with longevity. But a plant-based diet isn’t the only secret. In Sardinia, for example, meat and fish is consumed in moderation in addition to locally grown vegetables and <a href="https://journalofethnicfoods.biomedcentral.com/articles/10.1186/s42779-022-00152-5">traditional foods</a> such as acorn breads, pane carasau (a sourdough flatbread), honey and soft cheeses. Also observed in several blue zone areas is the inclusion of <a href="https://www.jacc.org/doi/10.1016/j.jacc.2021.10.041">olive oil</a>, <a href="https://pubmed.ncbi.nlm.nih.gov/33669360/">wine</a> (in moderation – around 1-2 glasses a day), as well as <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830687/">tea</a>. All of these contain powerful antioxidants which may help <a href="https://ncbi.nlm.nih.gov/pmc/articles/PMC10049696/">protect our cells</a> from damage <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273542/">as we age</a>. Perhaps then, it’s a combination of the protective effects of various nutrients in the diets of these centenarians, which explains their exceptional longevity. Another striking observation from these longevity hot spots is that meals are typically <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232892">freshly prepared at home</a>. Traditional blue zone diets also don’t appear to contain <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538973/">ultra-processed foods</a>, fast foods or sugary drinks which may <a href="https://pubmed.ncbi.nlm.nih.gov/32330232/">accelerate ageing</a>. So maybe it’s just as important to consider what these longer-living populations are not doing, as much as what they are doing. There also appears to be a pattern of eating until 80% full (in other words partial <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036399/">caloric reduction</a>. This could be important in also supporting how our cells deal with damage as we age, which could mean a longer life. Many of the factors making up these blue zone diets – primarily plant-based and natural whole foods – are associated with <a href="https://pubmed.ncbi.nlm.nih.gov/35706591/">lower risk of chronic diseases</a> such as <a href="https://pubmed.ncbi.nlm.nih.gov/28728684/">heart disease</a> and <a href="https://pubmed.ncbi.nlm.nih.gov/37589638/">cancer</a>. Not only could such diets contribute to a <a href="https://pubmed.ncbi.nlm.nih.gov/37836577/">longer, healthier life</a>, but could support a more <a href="https://pubmed.ncbi.nlm.nih.gov/33397404/">diverse gut microbiome</a>, which is also associated with healthy ageing. Perhaps then we can learn something from these remarkable centenarians. While diet is only one part of the bigger picture when it comes to longevity, it’s an area we can do something about. In fact, it might just be at the heart of improving not only the quality of our health, but the quality of how we age.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/221463/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/justin-roberts-1176632">Justin Roberts</a>, Professor of Nutritional Physiology, <a href="https://theconversation.com/institutions/anglia-ruskin-university-1887">Anglia Ruskin University</a>; <a href="https://theconversation.com/profiles/joseph-lillis-1505087">Joseph Lillis</a>, PhD Candidate in Nutritional Physiology, <a href="https://theconversation.com/institutions/anglia-ruskin-university-1887">Anglia Ruskin University</a>, and <a href="https://theconversation.com/profiles/mark-cortnage-438941">Mark Cortnage</a>, Senior Lecturer in Public Health and Nutrition, <a href="https://theconversation.com/institutions/anglia-ruskin-university-1887">Anglia Ruskin University</a> Image credits: Getty Images This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/people-in-the-worlds-blue-zones-live-longer-their-diet-could-hold-the-key-to-why-221463">original article</a>.

Food & Wine

The key decision that led to cruise passengers being abandoned by ship

A group of travellers, including two Australians, have been left stranded in Africa after their cruise ship allegedly refused to let them board the ship after a day trip. Eight passengers were among the many cruisers who disembarked the Norwegian Dawn at São Tomé and Príncipe, an island nation of 220,000 people off the west coast of Africa in the Gulf of Guinea, last Wednesday. The group of eight passengers took off on a private day tour, that reportedly wasn't organised through the cruise company. Things turned sour when the group were delayed on their day trip, with their tour operator allegedly connecting with the captain to tell the cruise the eight passengers would arrive later than their 3pm curfew. When the group arrived to the port, the ship was still anchored, but American couple Jill and Jay Campbell said the captain allegedly refused to let them on board. According to cruise ship lawyer Spencer Aonfeld, the group's big mistake was not booking the tour through the cruise company, as private tours come with a huge risk. Weighing into the drama on TikTok, Mr Aonfeld said, “Eight passengers were left behind when their cruise ship left them because they were delayed in an excursion apparently conducted without buying it directly through Norwegian." “These passengers include elderly passengers, one apparently a paraplegic, one has a heart condition, they don't have their medication, money, passports, cell phones and other things — they’re just left behind." “That unfortunately, according to Norwegian and me is, one of the consequences you pay when you buy your excursions from someone other than the cruise line." “Now they’re left there having to come up with the means to travel back to the next port or home and forfeit the remaining potion of their cruise. Imagine trying to do that in Africa without a passport, money or medication — we wish them the very best.” In order to rejoin the cruise and be reunited with their valuables, the group is now trekking to a port in Senegal, where the cruise is set to dock on Tuesday. In a statement, Norwegian Cruise Lines said it was “in communication with the guests,” and was providing them with “additional information” to rejoin the cruise. “While this is a very unfortunate situation, guests are responsible for ensuring they return to the ship at the published time, which is communicated broadly over the ship’s intercom, in the daily communication and posted just before exiting the vessel,” NCL said in a statement. The company said it was “working closely with the local authorities” on how the guests might re-join the ship. Image credits: Getty Images / WRAL North Carolina

Travel Trouble

Unimaginable scenes as Baltimore bridge collapses

The tranquil waters of Baltimore's Patapsco River turned tumultuous in the early hours of Tuesday following a catastrophic event that shook the city to its core. The aftermath of the Francis Scott Key Bridge collapse has left a community reeling, with one confirmed fatality and six individuals still missing as rescue efforts persist amid harrowing conditions. The calamity unfolded when a mammoth container ship lost power, careening into the Francis Scott Key Bridge on the US East Coast. The impact tore through the bridge's supports, sending vehicles and people plummeting into the frigid river below. In the chaos that ensued, heroes emerged as authorities swiftly responded, managing to halt traffic on the bridge, averting further catastrophe. However, the toll was already significant, with one individual confirmed dead and six others, believed to be part of a construction crew, still unaccounted for. As the day wore on, Baltimore City Fire Department Chief James Wallace provided updates on the situation, indicating that one survivor had been rescued and rushed to a local trauma centre in critical condition. Meanwhile, the US Coast Guard initiated a relentless search for the missing individuals, leveraging sonar technology to scour the depths of the river. The vessel responsible for the devastation, known as the Dali, was under the management of Synergy Marine Group, navigating under the Singapore flag. Although the crew and pilots were reported safe, the repercussions of the collision have reverberated far beyond the immediate vicinity. US President Joe Biden has pledged federal support for the reconstruction efforts: "This is going to take some time," he said. "The people of Baltimore can count on us, though, to stick with them at every step of the way until the port is reopened and the bridge is rebuilt." The collapse of the Francis Scott Key Bridge not only claimed lives but also severed a vital link in the region's infrastructure. The Port of Baltimore, a bustling gateway for maritime commerce, now faces significant disruption, with vessel traffic suspended indefinitely. The reverberations of this tragedy extend beyond Baltimore, with logistical challenges expected to ripple along the entire East Coast. As the day progressed, stories of resilience and compassion emerged. Retired Chief Donald Heinbuch, startled from his sleep by the rumbling impact, bore witness to the unimaginable destruction. "Never would you think that you would see physically see the Key Bridge tumble down like that - it looked like something out of an action movie," he said. "And you just think about, most importantly, which is what we all should be thinking about right now, nothing but those families and people that are impacted and those people who are risking their lives right now, for not just Baltimore City and Baltimore County but all over the state, to try to save lives. That should be our focus - the preservation of life. Because no one wants to see that happen, let alone someone in their family someone that they know, be injured in an incident like this." Baltimore Mayor Brandon Scott echoed the sentiments of a community in shock, emphasising the paramount importance of preserving life above all else. Images: Streamlive | 9News

Caring

Papa Swift vs Paparazzi: Taylor Swift's dad accused of assault

In the midst of celebrations marking the conclusion of Taylor Swift's Eras tour in Sydney, an unexpected and troubling incident has emerged involving her father – Scott Swift. The 71-year-old has been accused of assaulting an Australian photographer, Ben McDonald, in the early hours of Tuesday morning at a Sydney wharf in Neutral Bay. According to reports confirmed by NSW Police, the alleged altercation occurred around 2:30am, following Taylor Swift's final performance in the city. It's said that Taylor and her father had been enjoying post-show festivities when the incident took place, tarnishing what should have been a joyous occasion. McDonald, who serves as the chief executive of Matrix Media Group, recounted the events to <a href="https://www.dailymail.co.uk/tvshowbiz/article-13128721/Taylor-Swift-father-Scott-assault-photographer-Sydney-wharf.html" target="_blank" rel="noopener">Daily Mail Australia</a>, shedding light on the confrontation. He stated that Taylor and Scott arrived at the wharf after travelling from Homebush on a luxury superyacht named Quantum. McDonald claims that after they disembarked, Scott allegedly 'charged' at him. McDonald originally thought that it was a security guard, and was surprised when he realised it was Taylor's dad. "In 23 years of taking pictures, I have never seen anything like it," he told the Daily Mail. "He probably decided he needed to defend his daughter, for some reason... She got off the boat, she walked towards security guards who were shoving umbrellas in our faces, and then he charged." Footage capturing the moments leading up to and following the alleged assault has surfaced, providing some insight into the incident. <a href="https://www.dailymail.co.uk/tvshowbiz/article-13128721/Taylor-Swift-father-Scott-assault-photographer-Sydney-wharf.html" target="_blank" rel="noopener">The video</a> shows Taylor and her father walking up from the wharf, shielded by large umbrellas held by security guards. Amid the commotion, McDonald attempted to capture the scene, and was obstructed by the guards protecting Taylor and her companions, including Mr Swift. In the aftermath, McDonald reported the incident to authorities. He did not sustain serious injuries, though he described experiencing discomfort and soreness on the left side of his face. Images: YouTube

Legal

The secret witness who could be the key to the Madeleine McCann case

A secret witness to a disturbing comment made by the main suspect in the Madeleine McCann case could be the key to seeing him charged. Madeleine McCann was three years old when she went missing on a family trip to Portugal in 2007, and has not been seen since. Christian Brueckner, a convicted rapist and paedophile, has long been named the prime suspect in Maddie's abduction, and is set to stand trial on Friday for a series of charges, none of while relate to the McCann case. Now, almost seventeen years since her disappearance, a secret witness has come forward about a disturbing comment Brueckner a year after Maddie's abduction. Helge Busching, a former friend of Brueckner, has revealed a chilling conversation he had with his former friend after they ran into each other at a music festival. Busching, who is currently in police protection, claims Brueckner told him Madeleine was taken without anyone noticing because she didn't make a sound. "He said she didn't scream. 'She didn't scream', that is what Brueckner said and then I looked at Mr Brueckner and thought 'what are you telling me now?'" said Busching on <a href="https://9now.nine.com.au/60-minutes/the-secret-witness-who-could-break-open-the-madeleine-mccann-case/3a383ca7-758a-4b46-a288-8f911ee942e5" target="_blank" rel="noopener">60 Minutes</a>. <blockquote class="instagram-media" style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" data-instgrm-permalink="https://www.instagram.com/reel/C3NDFgEPudr/?utm_source=ig_embed&utm_campaign=loading" data-instgrm-version="14"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"> </div> </div> </div> <div style="padding: 19% 0;"> </div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"> </div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <div style="padding: 12.5% 0;"> </div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"> <div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"> </div> <div style="background-color: #f4f4f4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"> </div> <div style="background-color: #f4f4f4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"> </div> </div> <div style="margin-left: 8px;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"> </div> <div style="width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; transform: translateX(16px) translateY(-4px) rotate(30deg);"> </div> </div> <div style="margin-left: auto;"> <div style="width: 0px; border-top: 8px solid #F4F4F4; border-right: 8px solid transparent; transform: translateY(16px);"> </div> <div style="background-color: #f4f4f4; flex-grow: 0; height: 12px; width: 16px; transform: translateY(-4px);"> </div> <div style="width: 0; height: 0; border-top: 8px solid #F4F4F4; border-left: 8px solid transparent; transform: translateY(-4px) translateX(8px);"> </div> </div> </div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center; margin-bottom: 24px;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 224px;"> </div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 144px;"> </div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" href="https://www.instagram.com/reel/C3NDFgEPudr/?utm_source=ig_embed&utm_campaign=loading" target="_blank" rel="noopener">A post shared by 60 Minutes Australia (@60minutes9)</a> </div> </blockquote> In the wake of Busching's comments, the police prosecutor in Brueckner's case remains adamant he is behind the high-profile disappearance of Maddie. "We have evidence and we come to the conclusion that Madeleine McCann is dead and Christian B murdered her," says Hans Christian Wolters. With the 46-year-old currently in jail and facing convictions for several counts of rape and sexual assault, Wolters has the luxury of time to pursue all leads, no matter how small, to build a watertight case against the suspect. He said, "We have only one chance and we want to go to court with the best result we could get. So we decided to investigate as much as we can and if it takes much more time than normal investigations, it's the price for the best result." Image credits: Getty Images / 60 Minutes

Legal

Should we still be using RATs to test for COVID? 4 key questions answered

<a href="https://theconversation.com/profiles/hassan-vally-202904">Hassan Vally</a>, <a href="https://theconversation.com/institutions/deakin-university-757">Deakin University</a> We’re currently navigating <a href="https://www.thenewdaily.com.au/life/health/2023/11/15/covid-australia-eighth-wave">an eighth wave</a> of <a href="https://theconversation.com/were-in-a-new-covid-wave-what-can-we-expect-this-time-216820">COVID infections</a> in Australia. However the threat COVID poses to us is significantly less than it has ever been, thanks to immunity we’ve acquired through <a href="https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00801-5/fulltext">a combination</a> of prior infection and vaccination. That said, COVID is by no means behind us. The threat of severe illness remains higher for many people, and we’re all potentially at risk of developing <a href="https://www.health.gov.au/topics/covid-19/long-covid">long COVID</a>. While many people appear to be doing fewer rapid antigen tests (RATs) than they used to – if any at all – with rising cases, and as we head towards the festive season, testing continues to be important. So what do you need to know about testing in this wave? Here are four key questions answered. <h2>1. When should I do a RAT?</h2> There are a few situations where determining your COVID status is important to inform your actions, particularly during an uptick in infections. With more circulating virus, your index of suspicion that you have COVID if you’re experiencing cold-like symptoms should be higher. RATs work best when they’re used to confirm whether you have COVID when you <a href="https://www.tga.gov.au/products/covid-19/covid-19-tests/how-testing-works-covid-19">have respiratory symptoms</a> and are infectious. So the primary use of RATs should be to determine your COVID status when you’re sick. A positive test should prompt you to isolate, and if you’re eligible, to seek antivirals. Testing might also be worthwhile if you’ve come into contact with someone with COVID but you haven’t developed symptoms. If you find you have in fact contracted the virus, you can take steps to avoid spreading it to other people (you can infect others even <a href="https://www.healthline.com/health/what-is-asymptomatic-covid#prevalence">when you’re asymptomatic</a>). This is especially important if you’re going to be socialising in large groups or in contact with people who are vulnerable. Another situation in which to consider testing, particularly at this time of year, is before attending large social gatherings. While the reliability of a RAT is never perfect, do the test as close to the event as possible, because your disease status <a href="https://www.businessinsider.com/omicron-rapid-test-hour-before-party-not-day-before-expert-2021-12">can change quickly</a>. <h2>2. Should I test multiple times?</h2> Yes. RATs are not as sensitive as PCR tests, which is the trade-off we make for being able to do this test at home and <a href="https://www.wsj.com/articles/public-health-officials-pursue-covid-19-tests-that-trade-precision-for-speed-11599562800">getting a rapid result</a>. This means that while if you test positive with a RAT you can be very confident you have COVID, if you test negative, you cannot be as confident that you don’t have COVID. That is, the test may give you a false negative result. Although RATs from different manufacturers have different accuracies, all RATs approved by Australia’s Therapeutic Goods Administration must have a sensitivity of <a href="https://www.tga.gov.au/products/covid-19/covid-19-tests/covid-19-rapid-antigen-self-tests-home-use/covid-19-rapid-antigen-self-tests-are-approved-australia#:%7E:text=For%20rapid%20antigen%20tests%2C%20this,specificity%20of%20at%20least%2098%25.">at least 80%</a>. The way to increase your confidence in a negative result is to do multiple RATs serially – each negative test increases the confidence you can have that you don’t have COVID. If you have symptoms and have tested negative after your first RAT, <a href="https://www.fda.gov/medical-devices/safety-communications/home-covid-19-antigen-tests-take-steps-reduce-your-risk-false-negative-results-fda-safety">the advice</a> is to repeat the test after 48 hours, and potentially a third time after another 48 hours if the second test is also negative. <h2>3. Do RATs detect the latest variants?</h2> Since RATs <a href="https://www.healthdirect.gov.au/covid-19/testing#:%7E:text=Rapid%20antigen%20tests%2C%20or%20RATs,of%20proteins%20of%20the%20virus.">detect particular surface proteins</a> on SARS-CoV-2 (the virus that causes COVID), it’s theoretically possible that as the virus evolves, the reliability of these tests may be affected. However, RATs were designed to detect a part of the virus that is not as likely to mutate, so the hope is these tests <a href="https://www.health.com/do-covid-tests-work-new-variants-7967102">will continue to hold up</a> as SARS-CoV-2 evolves. The performance of RATs is continually being assessed by manufacturers. So far, there’s been no change reported in the ability of these tests to <a href="https://www.ama.com.au/articles/tga-updated-advice-rats-nearing-expiry-and-rats-efficacy-current-strains#:%7E:text=The%20TGA%20has%20received%20evidence,19%20RAT%20post%2Dmarket%20review.">detect the latest variants</a>. <h2>4. Can I rely on expired RATs?</h2> At this point in the pandemic, you might have a few expired tests at the back of your cupboard. Technically the most appropriate advice is to say you should never use a diagnostic test <a href="https://www.tga.gov.au/products/covid-19/covid-19-tests/covid-19-rapid-antigen-self-tests-home-use/covid-19-rapid-antigen-self-tests-are-approved-australia">past its expiry date</a>. As a general principle the performance of a test cannot be guaranteed beyond this date. The risk is that over time the components of the RAT degrade and if you use a test that’s not working optimally, it’s more likely to indicate <a href="https://www.health.com/can-you-use-expired-covid-test-6827970">you don’t have COVID</a> when you actually do, which may have consequences. However, as for all things COVID, the answer is not so black and white. Since these tests were new when they were introduced earlier in the pandemic, manufacturers didn’t have specific data on their performance over time, and so the expiry dates given were necessarily conservative. It’s likely these tests will work beyond the expiry dates on the packet, but just how long and how well they work is a bit of an unknown, so we need to be cautious. The other thing to consider is ensuring you store RATs correctly. Storage instructions should be found on the packet, but the key issue is making sure they’re not exposed to extreme temperatures. In particular, <a href="https://7news.com.au/lifestyle/health-wellbeing/how-to-properly-store-your-at-home-covid-19-rapid-antigen-tests-c-5465412">high temperatures</a> may damage the chemicals in the test which may reduce its sensitivity. <h2>The path from here</h2> Regular upticks in COVID cases are something we’re going to have to get used to. At these times, we should all be a bit more cautious about looking after ourselves and others as we go about our lives. What this looks like will vary for different people depending on their personal circumstances. However, being up to date with <a href="https://theconversation.com/what-are-the-new-covid-booster-vaccines-can-i-get-one-do-they-work-are-they-safe-217804">booster vaccinations</a>, having a plan for <a href="https://www.health.gov.au/topics/covid-19/oral-treatments">accessing antivirals</a> if you’re eligible, <a href="https://theconversation.com/with-covid-surging-should-i-wear-a-mask-217902">wearing masks</a> in high-risk settings and testing all continue to play an important role in responding to COVID.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/218016/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /> <a href="https://theconversation.com/profiles/hassan-vally-202904">Hassan Vally</a>, Associate Professor, Epidemiology, <a href="https://theconversation.com/institutions/deakin-university-757">Deakin University</a> Image credits: Getty Images This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/should-we-still-be-using-rats-to-test-for-covid-4-key-questions-answered-218016">original article</a>.

Body

Eight key questions about lab-grown meat

<div class="copy"> It’s been around for a decade now — but <a href="https://cosmosmagazine.com/podcast/lab-grown-meat/" target="_blank" rel="noreferrer noopener">cultured meat</a> still faces some huge hurdles. On 5 August, it will be ten years since the world was introduced to <a href="https://www.bbc.com/news/science-environment-23576143" target="_blank" rel="noreferrer noopener">the first lab-grown burger</a>. A decade after its arrival, biotechnologist Professor Paul Wood answers eight key questions about cultured meat. <h2>What is lab-grown meat?</h2> Cultured meat, also colloquially referred to as lab-grown meat, is <a href="https://academic.oup.com/af/article/13/2/68/7123477" target="_blank" rel="noreferrer noopener">the concept</a> of taking a biopsy from a living animal, selecting an individual cell type and growing these cells in large scale <a href="https://journals.physiology.org/doi/abs/10.1152/ajpcell.00408.2022" target="_blank" rel="noreferrer noopener">bioreactors</a>. Technically, it’s a viable alternative to growing an animal to maturity before harvesting meat from its carcass. Multiple cell types can be used from animals, such as muscle, fat or <a href="https://www.genome.gov/genetics-glossary/Fibroblast" target="_blank" rel="noreferrer noopener">fibroblasts</a>. The initial stage of cell selection requires the <a href="https://www.sciencedirect.com/science/article/pii/B9780123745538002537" target="_blank" rel="noreferrer noopener">creation of a cell line</a> which will grow continuously in a selective culture medium. <h2>How long has it been around?</h2> The technology for the culture of cells in laboratories has been used for many decades to produce drugs like <a href="https://www.cancer.gov/about-cancer/treatment/types/immunotherapy/monoclonal-antibodies" target="_blank" rel="noreferrer noopener">monoclonal antibodies</a> or <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7161866/" target="_blank" rel="noreferrer noopener">viral vaccines</a>. The difference with cultured meat is the cells themselves are used to produce edible products rather than used as production systems for monoclonals or viral antigens. Cultured meat was first introduced back in 2013 with <a href="https://www.bbc.com/news/science-environment-23576143" target="_blank" rel="noreferrer noopener">the unveiling of the world’s first lab-grown burger</a>, which cost a whopping USD$330,000 to produce. The first commercial cultured meat product was <a href="https://www.bbc.com/news/business-55155741" target="_blank" rel="noreferrer noopener">a chicken nugget licensed in Singapore</a> in 2020. <a href="https://www.scientificamerican.com/article/lab-grown-meat-approved-for-sale-what-you-need-to-know/" target="_blank" rel="noreferrer noopener">In June 2023</a>, the US Department of Agriculture granted two companies — Upside Foods and Good Meat — licences to sell chicken-based products. Significant excitement ensued in the food industry with <a href="https://www.liebertpub.com/doi/abs/10.1089/ind.2021.29240.ctu?journalCode=ind" target="_blank" rel="noreferrer noopener">predictions</a> that cultured meat will transform the meat industry by 2030. <h2>Is lab-grown meat commercially viable?</h2> Currently <a href="https://gfi.org/resource/cultivated-meat-eggs-and-dairy-state-of-the-industry-report/" target="_blank" rel="noreferrer noopener">around USD$3 billion</a> has been invested in over 150 companies working on beef, chicken, pork, lamb and exotic cell-based products. <a href="https://www.theatlantic.com/health/archive/2023/03/woolly-mammoth-meatball-stunt-food-marketing/673578/" target="_blank" rel="noreferrer noopener">Woolly mammoth meatball</a> anyone? Upside Foods has launched its <a href="https://edition.cnn.com/2023/07/01/business/lab-grown-chicken-san-francisco/index.html" target="_blank" rel="noreferrer noopener">new cell-based chicken product in a Michelin star restaurant</a>, but it is only available one night a month and the price has not been disclosed. Commercial success will require significant scaling in production, <a href="https://onlinelibrary.wiley.com/doi/full/10.1002/bit.27848" target="_blank" rel="noreferrer noopener">cost reductions</a> and consumer acceptance, or these products will be confined to niche markets for wealthy consumers. Cultured meat is unlikely to be the solution for the <a href="https://www.mdpi.com/2304-8158/6/7/53" target="_blank" rel="noreferrer noopener">increasing protein needs of developing nations</a>. The <a href="https://academic.oup.com/af/article/13/2/68/7123477" target="_blank" rel="noreferrer noopener">technical challenges</a> involve scaling up cell growth in over 10,000 litre fermentation vessels, while significantly reducing the cost of cell-culture media, the capital cost of equipment and the operating cost of high-quality sterile biocontainment facilities. It has been estimated that the cost of production of cultured meat <a href="https://cedelft.eu/publications/tea-of-cultivated-meat/" target="_blank" rel="noreferrer noopener">must be reduced by over 1,000-fold</a> to match that of conventional meat production. Proponents of cultured meat like to quote the concept of <a href="https://ourworldindata.org/moores-law" target="_blank" rel="noreferrer noopener">Moore’s law</a> that predicts that the cost of all new technology will be significantly reduced with time. However this law has never been applied to a biological system that has innate growth limits. <h2>Is it good for you — and does it taste okay?</h2> Currently <a href="https://www.nature.com/articles/s41467-020-20061-y" target="_blank" rel="noreferrer noopener">all cultured meats are hybrid or blended products</a>, in which the harvested cell paste — the meat component — is combined with plant-based materials, plus vitamins and minerals to produce burgers, meatballs, sausages and dumplings. Yes, you have to add the vitamins in, and no, you can’t make a steak with it yet. From a commercial perspective this is important, as cultured meat products will compete in the commodity meat market. Cultured meat does not produce a three-dimensional steak with multiple cell types and complex taste and texture. However, <a href="https://www.forbes.com/sites/lanabandoim/2021/02/12/worlds-first-3d-bioprinted-and-cultivated-ribeye-steak-is-revealed/?sh=4b6baf0a4781" target="_blank" rel="noreferrer noopener">there are companies</a> aiming to develop whole cuts of meat using 3D printing and bioengineering technology. <h2>What is the motivation to produce cell-cultured meat?</h2> The drivers for cultured meat are that <a href="https://www.abc.net.au/news/rural/2018-05-06/vegan-alternative-plant-based-meat-grown-in-lab/9726436" target="_blank" rel="noreferrer noopener">animals are not slaughtered</a>, there can be less land and water usage and less greenhouse gases are produced than conventional meat production, particularly from ruminants like cattle and sheep. A lower manufacturing footprint is a terrific plus. And not killing animals is something a lot of people advocate for, but until cultured meat has been scaled significantly, it won’t be known if it’s really better for the planet or for humans. The <a href="https://www.foodnavigator-usa.com/Article/2022/04/21/cultivated-meat-upside-foods-closes-400m-series-c-round-to-support-commercial-scale-plant-with-production-capacity-of-tens-of-millions-of-pounds" target="_blank" rel="noreferrer noopener">largest facility built so far</a> is a pilot plant in the USA that aims to produce around 1,000 pounds (approximately 450 kilograms) of product per week, which is equivalent to the dressed weight of three carcasses — what a single suburban butcher processes in one day. <h2>Will it be expensive to buy?</h2> The taste and texture of food is critical to consumers — but so is value for money. So, it’s not surprising <a href="https://www.visualcapitalist.com/cp/mapped-meat-consumption-by-country-and-type/" target="_blank" rel="noreferrer noopener">chicken is the dominant choice of meat</a> currently. With high-end lab-grown meat products, both taste and texture can most likely be matched, and with supplementation with vitamins like B12 it should be possible to make cultured meat nutritionally equivalent to its traditional counterpart too. However, cost will be a major challenge and sales data indicated that <a href="https://www.freshplaza.com/oceania/article/9535792/consumers-are-not-willing-to-pay-more-for-sustainability/" target="_blank" rel="noreferrer noopener">consumers will not pay any significant premium for slaughter-free or more sustainable products</a>. <h2>Who wants to eat meat grown in a factory?</h2> There are also questions around who the consumers will be for cultured meat. Vegans avoid animal products, vegetarians often reject the taste of meat and this new group of <a href="https://www.sciencedirect.com/science/article/pii/S0924224421003952" target="_blank" rel="noreferrer noopener">flexitarians</a>, while interested in trying new products, are seldom converted to <a href="https://www.foodnavigator.com/Article/2021/11/16/What-do-flexitarian-consumers-want-Plant-based-innovation-opportunities-revealed" target="_blank" rel="noreferrer noopener">regular customers</a>. In the US at least, this is one of the reasons that the many plant-based meat products have only captured <a href="https://gfi.org/marketresearch/#plant-based-meat" target="_blank" rel="noreferrer noopener">1.3 percent of the meat market</a>. It is also likely that plant-based products will be a <a href="https://www.mckinsey.com/industries/agriculture/our-insights/alternative-proteins-the-race-for-market-share-is-on" target="_blank" rel="noreferrer noopener">major competitor</a> to these new cultured meat products. <h2>Who will be next to approve cell-cultured meat?</h2> While the first cultured meat products have been licensed in Singapore and the US, it is expected more will follow from other regions. Even though <a href="https://www.fao.org/food-safety/scientific-advice/crosscutting-and-emerging-issues/cell-based-food/en/" target="_blank" rel="noreferrer noopener">a recent FAO report</a> identified over 50 potential health risks with cultured meat, it concluded that the overall risk was not greater than that seen with conventional meat products. There could be delays in Europe due to the conservative regulatory approach taken in the EU. In Australia, products are <a href="https://www.abc.net.au/news/rural/2023-06-27/cultured-lab-meat-to-sell-in-australia-to-rival-plant-based-meat/102527330" target="_blank" rel="noreferrer noopener">expected to be approved in 2024</a>. For now though? Well, the message to Aussie meat producers is … don’t sell the farm. Image credits: Getty Images </div> <div id="contributors"> <a href="https://cosmosmagazine.com/health/nutrition/explainer-lab-grown-meat/">This article</a> was originally published on <a href="https://cosmosmagazine.com">Cosmos Magazine</a> and was written by <a href="null">Cosmos</a>. </div>

Food & Wine

Gratitude amplified: Unlocking the key to happiness and deep connections

In today's fast-paced world, filled with negative news, challenging experiences, and personal losses, finding joy and gratitude can often be a difficult task. As we naturally tend to focus on the negative aspects of life, it becomes essential to pause and cultivate gratitude, which can have a profound impact on our lives and the lives of those around us. What is gratitude? Gratitude involves showing appreciation for the things in life that are important to you, and taking a moment to notice and acknowledge these moments have proven benefits of lifting mood and helping you feel more positive throughout the day. Have you ever stopped to notice that there is something to be grateful for every day if we just take stock? It could be a person who kindly let you merge into traffic, a refreshing breeze on a scorching day, a beautiful rainbow after a heavy downpour, or a thoughtful call or text from a friend. Gratitude is strongly and consistently associated with greater happiness. Gratitude helps people feel more positive emotions, relish good experiences, improve their health, deal with adversity, and build strong relationships. We also know that Gratitude begets gratitude, meaning that any kind act is likely to bring kindness back, in spades! Practice Gratitude – Write down 3 things per day <a href="https://theresilienceproject.com.au/">The Resilience Project</a> changed my life by introducing a simple practice: at the end of each day, we take five minutes to write down three things we are grateful for that happened that day. It could be as simple as a walk in the sun, a phone call from a friend, a stroll with your dog, or even a comforting cup of tea. Engaging in this exercise helps you articulate your gratitude and realise the abundance of things to be grateful for in our everyday lives. I personally experienced the transformative power of gratitude during the two years of COVID lockdown in Victoria while working full-time and home schooling my two boys, aged 8 and 10. Our family embraced this practice each night, which not only changed our outlook on life but also sparked positive conversations during dinner. Surprisingly, it was often the simplest things we were all grateful for, like homemade meals or cherished moments of togetherness. I distinctly remember preparing a hot meal and passing it over our neighbour's fence when their family was unwell with COVID. To our surprise, a few weeks later, they reciprocated with a homecooked meal. In those challenging times, a sense of community became such a source of positivity, and we were immensely grateful for the love that went into that dinner. So why not take the time to stop and smell the roses and practice gratitude? Who knows, over time, you may start to notice your stress levels decreasing, your relationships improving, and be blessed with a strengthened sense of community. Melissa Cutajar is <a href="https://www.connectedwomen.net/">Connected Women</a>’s Member Experience and Partnerships Manager. With a deep interest in health and wellness, Melissa is a source of positivity and creativity to the Connected Women team. <a href="http://connectedwomen.net/">Connected Women</a> provides a community for women over 50 to connect with each other and build meaningful friendships. With a rapidly growing communities in Perth, Sydney, Wollongong, and Melbourne, Connected Women provides a safe and welcoming space for women to come together and share experiences. To learn more about the organisation and how you can get involved, visit connectedwomen.net. Image credits: Getty Images

Relationships

Friends are key to keeping fit

Find yourself losing motivation with your workouts? An exercise buddy can be the best way to kick-start your fitness program and put the fun back into workouts. Here’s why you need an exercise buddy. Get motivated A partner can provide the motivation you need to get out and get active. When you’re tempted to stay in bed or flop on the couch, the influence of an exercise buddy will encourage you to change your mind – even if it’s just so you don’t disappoint them. Numerous studies have shown that having a partner increases the likelihood that you will stick to a fitness routine. Monitor your progress Sometimes it can be hard to see how far you’ve come if you’re exercising alone. Often it takes an independent party to see when you’ve gained strength or flexibility, toned up or increased your stamina. A buddy will help you recognise your achievements and celebrate them. Try new things It can be intimidating to go into a new fitness class or activity on your own. You might feel self conscious in front of others or not want to try that new machine without a bit of moral support. An exercise buddy takes the pressure off and brings a social element to the experience, so you can laugh at your mistakes or ask for help without judgment. Be competitive We’re not suggesting that your workouts need to be fights to the death, but having a buddy will inspire you to run that little bit further or push that little bit harder. You can both keep track of your progress against the other and work harder to keep improving. Because no one likes to fall behind. Safety first Exercising à deux is safer for everyone. It can be hard to listen to your own body and you might not be able to tell when something isn’t right. A buddy gives you a spotter when you’re lifting weights, someone to tell you if a pose looks like it’s placing too much strain in one area or just someone to help you home if you twist your ankle on a run. Another set of eyes helps prevent you exercising with bad form and makes sure you’re getting the most out of it. Laugh a little Above all, an exercise buddy makes working out more fun. You can catch up on gossip while walking, laugh at your novice yoga moves or grab a juice after swimming a few laps. And when something is fun you’re more likely to keep doing it. So buddy up! Image credits: Getty Images

Body

This eating habit is key to losing weight

New research has found the time of day you eat is key to losing weight. The findings reveal that your best efforts to cut back may prove ineffective if you’re not timing your meals correctly. A study found that mice lost weight when they were given a reduced calorie diet and only ate during the day. Rodents who consumed the same diet but ate at night did not reap the same results. Lead author of the study, Dr Joseph Takahashi, said, “Translated into human behaviour, these studies suggest that dieting will only be effective if calories are consumed during the daytime when we are awake and active.” Dr Takahashi added, “They further suggest that eating at the wrong time at night will not lead to weight loss even when dieting.” Scientists from the University of Texas Southwestern Medical Center also believe the timing of meals is important as it also affects circadian rhythms, the body’s 24-hour clock. They have highlighted how the research may explain how dietary habits impact lifespan. The study observed this by testing the day/night cycles of mice under different feeding schedules. Two groups of mice were fed at the wrong time during their normal cycle. One group was given 30 per cent less calories and the other group had unlimited food, but both groups were more active at night. Various research has associated sleep problems with an increased risk of obesity. “'It has been known for decades that calorie restriction prolongs lifespan in animals, but these types of studies are very difficult to conduct because they required manual feeding of subjects over many years," Dr Takahashi said “This automated system, which can be scaled up for large and very long longevity studies, provides the means to address open questions about what mechanisms extend lifespan in mammals.” Image credit: Shutterstock The research was published in the journal Cell Metabolism.

Body

Friends are key to keeping fit

Body

Italian historian makes major Mona Lisa breakthrough

A small town in Tuscany is revelling in excitement after it was claimed that a bridge in the backdrop of the Mona Lisa belongs to the town. Italian historian Silvano Vinceti determined that the bridge in the background of the most famous portrait in the world is in fact the Romito di Laterina bridge in the province of Arezzo: about 80km southeast of Florence. Leonardo da Vinci painted the masterpiece in Florence in the early 16th century, and ever since, it has been subject to disputes over the inspiration for the portrait. The identity of the woman in the painting - who is widely believed to be Lisa del Giocondo – has triggered as much speculation as the distant backdrop. Past theories have identified the bridge as Ponte Buriano, close to Laterina, as well as Ponte Bobbio in the northern Italian city of Piacenza. Using historical documents and drone images, and by making comparisons between the painting and photographs of the area, Vinceti said he is confident it was “the Etruscan-Roman bridge, Romito”. Vinceti told reporters in Rome that the most telling detail of the bridge’s identity is the number of arches. The bridge in Leonardo’s painting had four arches, as did the Romito. Ponte Buriano, on the other hand, has six arches, while Ponte Bobbio has more than six. Another telltale sign, according to Vinceti, is the fact that the bridge was once a “very busy, functioning bridge”, that provided a shortcut between Florence and Arezzo. Simona Neri, the mayor of Laterina, said Vinceti’s theory had caused a lot of excitement in the town of just over 3,500 people. She said, “We need to try to protect what’s left of the bridge.” Image credits: Getty Images

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Gratitude amplified: Unlocking the key to happiness and deep connections

Friends are key to keeping fit

This eating habit is key to losing weight

Friends are key to keeping fit

Italian historian makes major Mona Lisa breakthrough