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Squats and lunges might help you avoid knee surgery

<p>Whether it’s another round of squats and lunges, or a longer wall sit, researchers say working those quads could help lower your risk of a knee replacement.</p> <div> <p>In Australia, <a href="https://www.aihw.gov.au/reports/chronic-musculoskeletal-conditions/musculoskeletal-conditions/contents/arthritis" target="_blank" rel="noopener">about 9% of the population</a> has osteoarthritis, a condition known to lead to hip and knee surgery in severe cases. About 14 million Americans suffer from knee osteoarthritis, about half are expected to face knee replacement surgery. </p> <p>But new research offers hope, finding stronger quadricep muscles could play a role in avoiding knee replacement surgery.</p> <p>A study presented to <a href="https://press.rsna.org/timssnet/media/rsna/newsroom2023.cfm" target="_blank" rel="noopener">annual meeting</a> of the Radiological Society of North America, offers hope to people with arthritis, finding stronger quadriceps could help in avoiding a knee replacement.</p> <p>The two most important muscles in the knee are the extensors or quadriceps, and the hamstrings. Quads are the strong muscles located at the front of the thigh, which play a key role in gait. Hammies at the back of the thigh, are essential for hip and knee flexibility.</p> <p>The two muscles act as opposing forces, allowing physical activity while also protecting the knee. An imbalance can change the body’s biomechanics, and may progress to osteoarthritis.</p> <p>Using MRI scans – from the time of surgery as well as 2 and 4 years prior – researchers analysed thigh muscle volume in 134 participants from a national study called the Osteoarthritis Initiative. </p> <p>Using artificial intelligence to compute muscle volume from the MRI scans, the researchers compared 67 of the cohort who had a total, single knee replacement with 67 control participants who had not undergone knee replacement surgery.</p> <p>They found patients who had a higher ratio of quadricep to hamstring volume had significantly lower odds of a total knee replacement. Higher volume hamstrings were also associated with lower odds of surgery.</p> <p>The results suggest strength training – focusing on the quadriceps – may be beneficial, both in people with arthritis as well as the general population.</p> <p><!-- Start of tracking content syndication. Please do not remove this section as it allows us to keep track of republished articles --> <em><img id="cosmos-post-tracker" src="https://syndication.cosmosmagazine.com/?id=289325&amp;title=Squats+and+lunges+might+help+you+avoid+knee+surgery" width="1" height="1" loading="lazy" aria-label="Syndication Tracker" data-spai-target="src" data-spai-orig="" data-spai-exclude="nocdn" />Image credits: Getty Images</em></div> <div> </div> <div><em><a href="https://cosmosmagazine.com/health/body-and-mind/squats-and-lunges-might-help-you-avoid-knee-surgery/">This article</a> was originally published on <a href="https://cosmosmagazine.com">Cosmos Magazine</a> and was written by <a href="https://cosmosmagazine.com/contributor/petra-stock/">Petra Stock</a>. </em></div>

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The “unlikely culprit” worsening lung disease unequally

<p>Bronchiectasis (bron-kee-ek-tah-sis) is a chronic lung disease caused by widening of the airways in the lungs.</p> <p>As well as making breathing more difficult and coughing more common, it can lead to repeated flare-ups of lung infections.</p> <p>An international team of researchers based in Singapore has identified a bacteria, previously thought harmless in the lungs, that can be responsible for bronchiectasis flare-ups.</p> <p>According to their paper in Cell Host &amp; Microbe, Neisseria bacteria, and specifically the species Neisseria subflava, worsens bronchiectasis.</p> <p>Neisseria are known to cause meningitis and gonorrhoea, but  while they’d been found in lungs, they’ve previously not been thought to cause infections.</p> <p>“This discovery is significant because it can change how we treat our bronchiectasis patients with this bacterium,” says senior author Professor Sanjay Chotirmall, a researcher from the Lee Kong Chian School of Medicine at Nanyang Technical University, Singapore.</p> <p>“Doctors will now need to think about Neisseria as a potential ‘culprit’ in patients who are worsening despite treatment, and to conduct tests to identify those who may be harbouring this type of bacteria in their lungs.”</p> <p>While it affects people of every age and ethnicity, bronchiectasis prevalence increases as age does, and it’s up to four times more common among Asian people than white or black people.</p> <p>“We hope that early identification will lead to personalised therapy, and consequently, better disease outcomes for Asian patients with this devastating disease,” Chotirmall says.</p> <p>The researchers examined the lung microbiomes of 225 bronchiectasis patients from Singapore, Kuala Lumpur, and Dundee, in Scotland.</p> <p>They found that Neisseria subflava “dominated” the microbiome of Asian patients with worsening conditions.</p> <p>They then tested this bacteria in cell cultures and mice, showing that it caused cell disruption and thus inflammation and immune disfunction in lungs.</p> <p>“It is encouraging to see that we have made headway in identifying the Neisseria bacteria species as the cause of worsening bronchiectasis, the unlikely culprit that was originally not considered to be a threat,” says co-author Professor Wang De Yun, from the National University of Singapore’s Yong Loo Lin School of Medicine.</p> <p>“This comes as a strong reminder that we should not be too complacent when it comes to doing research and exercise more proactiveness in exploring various possibilities, as every seemingly innocent element could be a source of threat to our bodies and overall health.”</p> <p><strong>This article originally appeared on <a href="https://cosmosmagazine.com/health/bronchiectasis-lung-disease-bacteria/" target="_blank" rel="noopener">cosmosmagazine.com</a> and was written by Ellen Phiddian.</strong></p> <p><em>Image: Shutterstock</em></p>

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Lung cancer diagnosis on the rise in non-smokers

<p><span style="font-weight: 400;">With lung cancer coming in as the fifth most common type of cancer diagnosed in New Zealand, but ranking as the leading cause of cancer death, experts are calling for more research to help identify it in its early stages and determine risk factors in non-smokers.</span></p> <p><span style="font-weight: 400;">An example of a person with lung cancer, despite having never smoked, is US comedian Kathy Griffin who recently revealed she has been diagnosed with the cancer.</span></p> <p><span style="font-weight: 400;">Because the cancer was caught early and is confined to her left lung, the 60-year-old comedian will undergo surgery to remove half of her left lung.</span></p> <p><span style="font-weight: 400;">Following her surgery, Griffin is on the mend and keeping fans up-to-date with her recovery.</span></p> <blockquote style="background: #FFF; border: 0; border-radius: 3px; box-shadow: 0 0 1px 0 rgba(0,0,0,0.5),0 1px 10px 0 rgba(0,0,0,0.15); margin: 1px; max-width: 540px; min-width: 326px; padding: 0; width: calc(100% - 2px);" class="instagram-media" data-instgrm-captioned="" data-instgrm-permalink="https://www.instagram.com/p/CSSWpL7hcRz/?utm_source=ig_embed&amp;utm_campaign=loading" data-instgrm-version="13"> <div style="padding: 16px;"> <div style="display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #f4f4f4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"></div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"></div> <div style="background-color: #f4f4f4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"></div> </div> </div> <div style="padding: 19% 0;"></div> <div style="display: block; height: 50px; margin: 0 auto 12px; width: 50px;"></div> <div style="padding-top: 8px;"> <div style="color: #3897f0; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: 550; line-height: 18px;">View this post on Instagram</div> </div> <p style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; line-height: 17px; margin-bottom: 0; margin-top: 8px; overflow: hidden; padding: 8px 0 7px; text-align: center; text-overflow: ellipsis; white-space: nowrap;"><a style="color: #c9c8cd; font-family: Arial,sans-serif; font-size: 14px; font-style: normal; font-weight: normal; line-height: 17px; text-decoration: none;" rel="noopener" href="https://www.instagram.com/p/CSSWpL7hcRz/?utm_source=ig_embed&amp;utm_campaign=loading" target="_blank">A post shared by Kathy Griffin (@kathygriffin)</a></p> </div> </blockquote> <p><span style="font-weight: 400;">Griffin isn’t alone either, with a growing number of people receiving a lung cancer diagnosis without ever smoking.</span></p> <p><strong>Not just a “smoker’s disease”</strong></p> <p><span style="font-weight: 400;">Though smoking is one of the largest risk factors for lung cancer, the proportion of those diagnosed with the disease who are “never-smokers” is increasing.</span></p> <p><span style="font-weight: 400;">According to Health Navigator New Zealand, one in five New Zealanders who have been diagnosed with the condition were life-long non-smokers.</span></p> <p><span style="font-weight: 400;">This increase in the condition has been seen in other countries with a </span><a rel="noopener" href="https://pubmed.ncbi.nlm.nih.gov/28132018/" target="_blank"><span style="font-weight: 400;">2017 study</span></a><span style="font-weight: 400;"> of lung cancer patients in US hospitals finding the percentage of never-smokers increased from eight percent in 1990 to 1995, to 14.9 percent from 2011 to 2013.</span></p> <p><span style="font-weight: 400;">Surgeon Andrew Kaufman, whose program for never-smokers at Mount Sinai Hospital in New York has treated 3,800 patients in 10 years, said: “Since the early 2000s, we have seen what I think is truly an epidemiological shift in lung cancer.”</span></p> <p><span style="font-weight: 400;">“It is well-documented that approximately 20 percent of lung cancer cases that occur in women in the US and nine percent of cases in men, are diagnosed in never-smokers,” he confirmed.</span></p> <p><span style="font-weight: 400;">However, the reasons why more people are being diagnosed without smoking is not well known.</span></p> <p><strong>More research is needed</strong></p> <p><span style="font-weight: 400;">Dr Marianne Weber, a senior research fellow at the Daffodil Centre, is overseeing a new study to identify potential risk factors for those who don’t smoke.</span></p> <p><span style="font-weight: 400;">By poring over two large population studies in Australia and China, the researchers are looking to link lung cancer to factors such as diet, lifestyle, and household air pollution.</span></p> <p><span style="font-weight: 400;">“If we can highlight a risk profile for someone who might go on to develop lung cancer when they’re a non-smoker, that would be ideal,” Dr Weber said.</span></p> <p><span style="font-weight: 400;">So far, cancer doctors have found one group of people who are more at risk: women.</span></p> <p><span style="font-weight: 400;">Worldwide, half of female lung cancer patients have never smoked, while only 15 percent of male lung cancer patients are never-smokers.</span></p> <p><span style="font-weight: 400;">Josephine Feliciano, an oncologist at Johns Hopkins University School of Medicine, said that, beyond sex, “nothing stands out as a single large risk factor” for lung cancer in non-smokers.</span></p> <p><span style="font-weight: 400;">“But air pollution, radon, family history of lung cancer, [and] genetic predispositions [all play a role],” Feliciano said.</span></p> <p><span style="font-weight: 400;">Additionally, chronic lung infections and lung diseases such as chronic obstructive pulmonary disorder (COPD) seems to increase the risk of diagnosis.</span></p> <p><span style="font-weight: 400;">“Of all the patients that present with the disease, the current survival rate is only about 17 percent,” said Dr Stirling, a senior respiratory specialist at The Alfred Hospital and leader of the Victorian Lung Cancer Registry.</span></p> <p><span style="font-weight: 400;">“For patients with stage four disease the median survival, so that’s the time at which 50 percent of patients will succumb to the disease, is somewhere between seven and 12 months.”</span></p>

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The finger trick that could help detect lung cancer

<p><span>An expert has revealed a simple “finger trick” that could help uncover respiratory tumours.</span></p> <p><span>According to <a href="https://au.lifestyle.yahoo.com/finger-trick-that-could-diagnose-lung-cancer-201753189.html"><em>Bupa UK</em></a>’s oncology nurse advisor Emma Norton, people can do this by bringing the nails of their index fingers together as if making the top of the heart.</span></p> <p><span>A diamond-shaped gap should be visible between the nails, Norton said. If this is missing, it could be a sign of finger clubbing or a deformity of the fingers and fingernails, which may indicate serious diseases such as lung cancer.</span></p> <p><span>The symptom occurs in 35 percent of people with lung cancer, according to <a href="https://www.cancerresearchuk.org/about-cancer/mesothelioma/symptoms/finger-clubbing"><em>Cancer Research UK</em></a><em>.</em></span></p> <p><iframe src="https://www.facebook.com/plugins/post.php?href=https%3A%2F%2Fwww.facebook.com%2Fphoto.php%3Ffbid%3D10160673422260207%26set%3Dp.10160673422260207%26type%3D3%26theater&amp;width=500&amp;show_text=true&amp;height=741&amp;appId" width="500" height="741" style="border: none; overflow: hidden;" scrolling="no" frameborder="0" allowtransparency="true" allow="encrypted-media"></iframe></p> <p><span>“The test is used by medical professionals as a partial method of confirming conditions, but you can also do the test yourself, and it only takes a few seconds,” Norton said.</span></p> <p><span>“If you can’t see any kind of gap beneath your nail beds, this means your fingers are clubbed.”</span></p> <p><span>A <a href="https://www.sciencedaily.com/releases/2008/05/080529163120.htm">study by researchers at the University of Leeds</a> found that tumour in the lungs may lead to the overproduction of a fatty compound called PGE2, which results in clubbing.</span></p> <p><span>“There are benign cases of clubbing, where it isn’t associated with other illnesses, but particularly because of the link to lung cancer, it is generally regarded as rather sinister,” said Professor David Bonthron of the Leeds Institute of Molecular Medicine.</span></p> <p><span>Norton recommends that people who do the test and uncover clubbing need to see their GP as soon as possible.</span></p>

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The worrying link between blood pressure medication and lung cancer

<p>A new study has found that popular blood pressure pills taken by millions over the world could increase the risk of lung cancer.</p> <p>The research has shone a spotlight on how ACE inhibitors are more likely to develop cancer than other types of drugs.</p> <p>The study, conducted by researchers at McGill University in Montreal, Canada, said the risk of the medication increased the longer patients were taking it.</p> <p>Those taking the drug for five years were 22 per cent more likely to get lung cancer, while those who had been on it for 10 years were 31 per cent more likely.</p> <p>Scientists believe the drug causes the accumulation of chemicals called bradykinin on the lung, which can cause cancer.</p> <p>However, other experts have cast doubt on the shock findings, saying that the lung cancer could instead be caused by patients smoking at the same time as the drugs.</p> <p>Up to five million patients in the UK take ACE inhibitors, with most patients being prescribed the medication for high blood pressure or following a heart attack.</p> <p>It is branded as Tritace in the UK but sold as Altace in the US.</p> <p>Other common names for the drug include captopril, cilazapril, ramipril and enalapril.</p> <p style="text-align: center;"><img style="width: 500px; height: 281.25px;" src="https://oversixtydev.blob.core.windows.net/media/7821634/image_.jpg" alt="" data-udi="umb://media/22c827b8509a4ceca6b6dc849dd73dcf" /></p> <p>The medication works by reducing the activity of the angiotensin-converting enzyme (ACE).</p> <p>After this enzyme is blocked, the blood vessels relax and widen, thus lowering the blood pressure.</p> <p>The study was published in the BMJ and analysed data from 992,000 adults who were prescribed blood pressure drugs in the UK between 1995 and 2015.</p> <p>Patients were either taking ACE inhibitors or angiotensin receptor blockers, which lower blood pressure in a different way.</p> <p>Compared to patients on angiotensin, those on ACE inhibitors were 14 per cent more likely to be diagnosed with lung cancer over a six-year period.</p> <p>The researchers have called for “additional studies, with long term follow-up, to investigate the effects of these drugs on incidence of lung cancer”.</p> <p>Although a 14 per cent increased risk might not appear to be much, “small relative effects could translate into large absolute numbers of patients at risk for lung cancer”.</p> <p>The researchers added: “Given the potential impact of our findings, they need to be replicated in other settings, particularly among patients exposed for longer durations.”</p> <p>However, Professor Stephen Evans, an expert on the effects of drugs at the London School of Hygiene and Tropical Medicine, said it was unlikely the drugs were causing lung cancer.</p> <p>“Drawing strong conclusions and talking about public health impact in this situation seems premature,” he said.</p> <p>Do you take blood pressure tablets? Let us know in the comments below.</p>

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The best way to keep your lungs healthy

<p>It's a spectacular phenomenon that we rarely stop to consider. Every one of the 23,000-odd breaths we take each day pumps oxygen to the 37.2 trillion cells that create our body.</p> <p>"Normal breathing is automatic, we don't have to think about it," says Jennifer Alison, a Professor of Respiratory Physiotherapy at Australia's University of Sydney. "If you are healthy, it shouldn't be of concern to you."</p> <p>Rather, when we need more oxygen, our body lets us know, often with a sigh or a yawn. Or, when we exercise, our muscles produce more carbon dioxide (metabolic waste) which stimulates receptors to take in more oxygen.</p> <p>"The reason why we take that breath is to maintain carbon dioxide at a certain level," Alison explains. "All the cells in the body operate at a certain acidity.</p> <p>“It's a nice balance – getting rid of the carbon dioxide and also giving your cells enough oxygen.</p> <p>The nice, rhythmic balance of breathing in and out is thrown out however by certain factors – like anxiety, ageing, lung disease, being tense, having poor posture, and not stretching.</p> <p>Anxiety, for instance, can cause the muscles around the throat to contract, making it feel like breathing is constricted. Interestingly, although our throat can feel tight, anxiety opens up our lungs.</p> <p>"When you are anxious there's the tendency to over breathe – it's the flight or fight thing – where the adrenaline rush makes your airways open up," Alison says.</p> <p>Ageing can also affect breathing as the lungs get "floppier" and people don't expand fully, while lung diseases, where the airways or lungs are damaged can restrict the ability to breathe properly.</p> <p>These factors may make us more conscious of our breath – or our inability to breathe properly – so we might think that taking deeper breaths is the answer.</p> <p>Certainly, breathing techniques have been used for centuries by yogis to elicit certain effects on the mind and body.</p> <p>Breathing well can help us to manage stress and anxiety, increase energy levels and help us relax and even help us to fall asleep in one minute.</p> <p>Not smoking is another obvious answer, but if you want to breathe well and maintain good lung health, you might be surprised about what the answer is.</p> <p>"The best way to maintain lung health is to stay active, don't be sedentary," Alison says. "You need to move every 20 minutes."</p> <p>The more muscles are deconditioned through a lack of exercise, the less efficient they are, which produces more carbon dioxide and therefore drives breathing even more as our bodies try to regain balance of oxygen and carbon dioxide, Alison explains.</p> <p>For this reason, exercise is important for both healthy people and even those with lung disease.</p> <p>"We treat our [lung disease] patients like athletes – if you're a marathon runner, with lots of training you develop more blood vessels around the muscles which deliver more oxygen," Alison says of patients with lung disease.</p> <p>"We want to get those changes in their muscles ... after a programme – working at the same level of exercise, they can do it with less breath."</p> <p>And with less effort and breath, we can all breathe easier by keeping these tips in mind.</p> <p>We breathe through the nose because it warms, filters, and moistens the air before it reaches the lungs. We miss these advantages when we breathe through the mouth.</p> <p>"It is a myth that 'deep' breathing – that is, 'big, large-volume' breathing – is good for you," says breathing expert and physiotherapist, Tess Graham.</p> <p>"This belief may well qualify as public health enemy number one! The three big flaws in the advice to breathe deeply are that people tend to increase their breath size far above normal, dump out too much carbon dioxide and worst of all, believe that it is good for them to do so. This is a recipe for hypoxia – reduced oxygen in your cells. (When carbon dioxide drops too far, blood vessels narrow and restrict blood flow to vital organs and oxygen uptake by your cells goes down)."</p> <p>It is not a case of the more oxygen, the better. "We normally breathe in far more oxygen than we need or can use," Graham says. "With normal breathing, a healthy person's blood is already 97 to 99 per cent saturated with oxygen."</p> <p>If you suffer anxiety, Alison says: "If you get people to take big, deep breaths they can overdo it. You're blowing off carbon dioxide more which can make you feel light-headed or dizzy." Instead, she suggests holding the breath for a second or two. "It reduces the rate of the breath – it's a balance of rate and depth – and lets the carbon dioxide rise back," Alison says.</p> <p>"Sighing out quietly and relaxing your muscles can also help."</p> <p>How often do you exercise? Let us know in the comments below.</p> <p><em>Written by Sarah Berry. First appeared on <a href="http://Stuff.co.nz" target="_blank"><strong><span style="text-decoration: underline;">Stuff.co.nz.</span></strong></a></em></p> <p><strong>Related links:</strong></p> <p><a href="/health/body/2016/08/myths-of-modern-health/"><em><strong><span style="text-decoration: underline;">Debunking 5 myths of modern health</span></strong></em></a></p> <p><a href="/health/body/2016/08/foods-that-boost-your-body-heat/"><strong><em><span style="text-decoration: underline;">6 foods that boost your body heat</span></em></strong></a></p> <p><a href="/health/body/2016/07/expert-tips-to-manage-type-2-diabetes/"><em><strong><span style="text-decoration: underline;">Expert tips to manage type 2 diabetes</span></strong></em></a></p>

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