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Common drug shows potential in reversing ageing

<p>A common medication has been found to have anti-ageing qualities, with scientists finding that the drug can de-age monkeys. </p> <p>Metformin, a cheap and common diabetes drug that has been used since the 1950s, could be an anti-ageing elixir, with scientists from the Chinese Academy of Sciences and Beijing Institute of Genomics using the pill to "markedly" slow down ageing in the animals.</p> <p>According to the experts, the medication reduced deterioration of the brain and boosted cognitive abilities in the primates while also slowing down bone loss and aiding in the "rejuvenation" of several tissues and organs. </p> <p>The most significant improvements were seen in the liver and frontal lobe, the part of the brain responsible for language, reasoning, problem solving, memory, movement and personality. </p> <p>Researchers said all of the findings led to the conclusion that "metformin can reduce biological age indicators" up to six years, with the medication paving the way for ageing reversal in humans.</p> <p>The drug was previously tested on mice, but since testing the medication on Cynomolgus monkeys - that are both physiologically and functionally similar to humans - the tests have shown more promise for potential human trials. </p> <p>The researchers said of the 40-month study, "Our research pioneers the systemic reduction of multi-dimensional biological age in primates through metformin, paving the way for advancing pharmaceutical strategies against human ageing."</p> <p>The scientists added, "[The study] represents an important advance in the quest to delay human ageing, with geriatric medicine research gradually shifting its focus from treating individual chronic diseases to systemic intervention against ageing."</p> <p><em>Image credits: Shutterstock </em></p>

Body

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You can’t reverse the ageing process but these 5 things can help you live longer

<p><em><a href="https://theconversation.com/profiles/hassan-vally-202904">Hassan Vally</a>, <a href="https://theconversation.com/institutions/deakin-university-757">Deakin University</a></em></p> <p>At this time of year many of us resolve to prioritise our health. So it is no surprise there’s a <a href="https://digiday.com/marketing/health-food-brands-ramp-up-marketing-efforts-around-consumers-new-years-resolutions/">roaring trade</a> of products purporting to guarantee you live longer, be healthier and look more youthful.</p> <p>While an <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822264/">estimated</a> 25% of longevity is determined by our genes, the rest is determined by what we do, day to day.</p> <p>There are no quick fixes or short cuts to living longer and healthier lives, but the science is clear on the key principles. Here are five things you can do to extend your lifespan and improve your health.</p> <h2>1. Eat a predominantly plant-based diet</h2> <p>What you eat has a huge impact on your health. The evidence overwhelmingly <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8210981/#:%7E:text=According%20to%20an%20expansive%20review,13%20Given%20that%20so%20many">shows</a> eating a diet high in plant-based foods is associated with health and longevity.</p> <p>If you eat more plant-based foods and less meat, processed foods, sugar and salt, you reduce your risk of a range of illnesses that shorten our lives, including heart disease and cancer.</p> <p>Plant-based foods <a href="https://www.nature.com/articles/s41398-019-0552-0">are rich</a> in nutrients, phytochemicals, antioxidants and fibre. They’re also anti-inflammatory. All of this protects against damage to our cells as we age, which helps prevent disease.</p> <p>No particular diet is right for everyone but one of the most studied and <a href="https://www.hsph.harvard.edu/nutritionsource/healthy-weight/diet-reviews/mediterranean-diet/#:%7E:text=%5B6%5D%20Those%20who%20had%20the,who%20had%20the%20lowest%20adherence.">healthiest</a> is the <a href="https://www.eatingwell.com/article/291120/mediterranean-diet-for-beginners-everything-you-need-to-get-started/">Mediterranean diet</a>. It’s based on the eating patterns of people who live in countries around the Mediterranean Sea and emphases vegetables, fruits, wholegrains, legumes, nuts and seeds, fish and seafood, and olive oil.</p> <h2>2. Aim for a healthy weight</h2> <p>Another important way you can be healthier is to try and achieve a healthy weight, as obesity <a href="https://www.healthline.com/health/obesity/how-obesity-affects-body">increases the risk</a> of a number of health problems that shorten our lives.</p> <p>Obesity puts strain on all of our body systems and has a whole myriad of physiological effects including causing inflammation and hormonal disturbances. These <a href="https://www.ncbi.nlm.nih.gov/books/NBK572076/">increase your chances</a> of a number of diseases, including heart disease, stroke, high blood pressure, diabetes and a number of cancers.</p> <p>In addition to affecting us physically, obesity is also <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052856/">associated with</a> poorer psychological health. It’s linked to depression, low self-esteem and stress.</p> <p>One of the biggest challenges we face in the developed world is that we live in an <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817492/">environment</a> that promotes obesity. The ubiquitous marketing and the easy availability of high-calorie foods our bodies are hard-wired to crave mean it’s easy to consume too many calories.</p> <h2>3. Exercise regularly</h2> <p>We all know that exercise is good for us – the <a href="https://www.insurancebusinessmag.com/au/news/breaking-news/hcf-reveals-australias-most-popular-new-years-resolutions-for-2023-431665.aspx">most common resolution</a> we make this time of year is to do more exercise and to get fitter. Regular exercise <a href="https://www.who.int/news-room/fact-sheets/detail/physical-activity">protects</a> against chronic illness, lowers your stress and improves your mental health.</p> <p>While one of the ways exercising helps you is by supporting you to control your weight and lowering your body fat levels, the <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1402378/#:%7E:text=For%20instance%2C%20routine%20physical%20activity,HDL%5D%20cholesterol%20levels%20and%20decreased">effects</a> are broader and include improving your glucose (blood sugar) use, lowering your blood pressure, reducing inflammation and improving blood flow and heart function.</p> <p>While it’s easy to get caught up in all of the hype about different exercise strategies, the evidence <a href="https://www.medicalnewstoday.com/articles/320760">suggests</a> that any way you can include physical activity in your day has health benefits. You don’t have to run marathons or go to the gym for hours every day. Build movement into your day in any way that you can and do things that you enjoy.</p> <h2>4. Don’t smoke</h2> <p>If you want to be healthier and live longer then don’t smoke or vape.</p> <p>Smoking cigarettes affects almost every organ in the body and is associated with both a shorter and lower quality of life. There is no safe level of smoking – every cigarette increases your <a href="https://theconthatkills.org.au/?utm_source=googlesearch&amp;utm_medium=search&amp;utm_campaign=theconthatkills23&amp;utm_content=RSA&amp;gclid=Cj0KCQjwqP2pBhDMARIsAJQ0Czrlep6EQHC-8_9xUhpz0h9v2ZglMF-6-k7_65awq8FxVaIL5HRoivwaAqJwEALw_wcB&amp;gclsrc=aw.ds">chances of developing</a> a range of cancers, heart disease and diabetes.</p> <p>Even if you have been smoking for years, by giving up smoking at any age you can experience <a href="https://www.cdc.gov/tobacco/quit_smoking/how_to_quit/benefits/index.htm">health benefits</a> almost immediately, and you can reverse many of the harmful effects of smoking.</p> <p>If you’re thinking of switching to vapes as a healthy long term option, <a href="https://theconversation.com/can-vaping-help-people-quit-smoking-its-unlikely-204812">think again</a>. The long term health effects of vaping are not fully understood and they come with their own <a href="https://theconversation.com/no-vapes-arent-95-less-harmful-than-cigarettes-heres-how-this-decade-old-myth-took-off-203039">health risks</a>.</p> <h2>5. Prioritise social connection</h2> <p>When we talk about living healthier and longer, we tend to focus on what we do to our physical bodies. But one of the most important discoveries over the past decade has been the recognition of the importance of spiritual and psychological health.</p> <p>People who are lonely and socially isolated have a much higher risk of dying early and are <a href="https://healthnews.com/longevity/healthspan/social-connection-and-longevity/#:%7E:text=One%20of%20the%20biggest%20benefits,the%20following%20factors%20and%20influences.">more likely</a> to suffer from heart disease, stroke, dementia as well as anxiety and depression.</p> <p>Although we don’t fully understand the mechanisms, it’s likely due to both behavioural and biological factors. While people who are more socially connected are <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150158/">more likely</a> to engage in healthy behaviours, there also seems to be a more direct physiological effect of loneliness on the body.</p> <p>So if you want to be healthier and live longer, build and maintain your connections to others.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/214580/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /></p> <p><a href="https://theconversation.com/profiles/hassan-vally-202904"><em>Hassan Vally</em></a><em>, Associate Professor, Epidemiology, <a href="https://theconversation.com/institutions/deakin-university-757">Deakin University</a></em></p> <p><em>Image credits: Getty Images</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/you-cant-reverse-the-ageing-process-but-these-5-things-can-help-you-live-longer-214580">original article</a>.</em></p>

Caring

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These 10 smart grocery swaps can help reverse diabetes

<p><strong>Diagnosis diabetes</strong></p> <p>It can feel daunting to be faced with the need to make a major lifestyle change. You enjoy food, and you should. At Reader’s Digest, we like to think nature designed nutrition to taste delicious so it can be a source of pleasure in your day that’s fun to look forward to.</p> <p>If you’ve been diagnosed with diabetes or pre-diabetes, this diagnosis doesn’t have to take over your whole identity and all the things that bring you joy. There are ways to adapt some of your favourite foods so you can still have them!</p> <p>Registered dietitian Jackie Newgent lists interesting meal swaps you can make so that classic dishes can be healthier, while still plenty pleasurable.</p> <p>With some wisdom and dedication, it can be possible to turn your condition around and feel great for good.</p> <p><strong>Pair starchy with non-starchy veggies</strong></p> <p><span style="text-decoration: underline;"><em>Instead of:</em></span> one kilo potatoes</p> <p><span style="text-decoration: underline;"><em>Buy:</em></span> 500g kilo potatoes plus 500g cauliflower</p> <p>This mashed potato hack keeps your total carbs in check without forgoing flavour. Whip equal parts boiled potatoes together with roasted or boiled cauliflower. </p> <p>The results of this dynamic duo may help you better manage your blood glucose, since they’re carb-friendlier than a huge bowl of mashed potatoes alone: 100 grams of cooked potatoes without skin provides 22 grams of total carbohydrates, versus 13 grams total carbohydrate in the 100 gram combination of cooked potatoes and cauliflower.</p> <p><strong>Pick fruit you can chew</strong></p> <div> <p><span style="text-decoration: underline;"><em>Instead of:</em></span> one litre apple juice</p> <p><span style="text-decoration: underline;"><em>Buy:</em></span> one bag of apples</p> <p>Enjoy whole fruit rather than just the juice whenever possible to get all the fibre of the naturally sweet fruit with its edible peel…plus chewing satisfaction. One medium apple contains 4.4 grams of fibre while a 200ml glass or juice box of 100-percent apple juice has 0.4 grams of fibre. </p> <p>The soluble fibre in apples can help slow down absorption of sugars. Polyphenols in apples may have powerful antioxidant properties.</p> <p><strong>Grill a better burger</strong></p> <p><span style="text-decoration: underline;"><em>Instead of:</em></span> 500g 85% lean ground beef patties</p> <p><span style="text-decoration: underline;"><em>Buy:</em></span> 500g ground chicken breast</p> <p>Gram for gram, chicken breast has significantly less saturated fat than the marbly beef of classic burgers. Specifically, an 85g cooked 85% lean ground beef patty has five grams of saturated fat compared to 0.6 grams of saturated fat for a cooked patty made from 85g of chicken breast meat.</p> <p>Keeping saturated fat intake low is especially important when you have diabetes to help keep your heart healthy. Pro-tip: make chicken burgers juicier and tastier by combining ground chicken breast with a little plain yogurt, rolled oats, and herbs and spices before cooking.</p> <p><strong>Look for live cultures in the dairy section</strong></p> <p><span style="text-decoration: underline;"><em>Instead of:</em></span> one container regular cottage cheese</p> <p><span style="text-decoration: underline;"><em>Buy:</em></span> one container plain low-fat Greek yogurt or cultured cottage cheese</p> <p>Probiotics are “good” bacteria that help keep your gut healthy. For people with type 2 diabetes, research published in Advances in Nutrition suggested that probiotics may also have glucose-lowering potential. So, pop products with live active cultures (probiotics) into your cart while strolling by the dairy aisle. Choose plain low-fat Greek yogurt or cultured cottage cheese.</p> <p>Be sure to read the nutrition labels, since probiotics aren’t in all dairy foods. And, for the lower-sodium pick, stick with yogurt.</p> <p><strong>Choose healthier-sized grain portions </strong></p> <p><span style="text-decoration: underline;"><em>Instead of:</em></span> 1/2 dozen bakery-style plain bagels</p> <p><span style="text-decoration: underline;"><em>Buy:</em></span> one package of wholegrain English muffins</p> <p>Swapping wholegrain in place of refined grain products helps kick up fibre and other plant nutrients. Studies suggests this is linked to lower risk of type 2 diabetes. Also, opting for healthier-sized varieties, such as wholegrain English muffins rather than big bakery-style plain bagels helps cut kilojoules (and carbs) – not enjoyment – while promoting a healthier weight. In fact, you’ll slash over 1000 kilojoules by enjoying a whole-wheat English muffin instead of that oversized 140g bagel.</p> <p><strong>Get your munchies with benefits </strong></p> <p><span style="text-decoration: underline;"><em>Instead of:</em></span> one bag of potato chips</p> <p><span style="text-decoration: underline;"><em>Buy:</em></span> one jar or bulk-bin container of roasted peanuts</p> <p>It’s a no-brainer: a small handful of nuts is a better bet than potato chips. Peanuts, for instance, offer a triple whammy of dietary fibre, plant protein and healthy fat, which can boost satiety. Greater satisfaction means a greater chance you’ll keep mealtime portions right-sized.</p> <p>When peanuts or other nuts are eaten along with carb-rich foods, they can help slow down the blood sugar response. Plus, a Mediterranean study found that higher nut consumption may be associated with better metabolic status.</p> <p><strong>Dress a salad smartly </strong></p> <p><span style="text-decoration: underline;"><em>Instead of:</em></span> one bottle of fat-free salad dressing</p> <p><span style="text-decoration: underline;"><em>Buy:</em></span> one small bottle olive oil plus one small bottle balsamic or red wine vinegar</p> <p>Some bottled salad dressings can trick you. For instance, “fat-free” salad dressing may be loaded with added sugars. (For reference: four grams of sugar is equal to one teaspoon.)</p> <p>So, read salad dressing labels carefully for sneaky ingredients, especially excess salt (over 250 milligrams of sodium per two-tablespoon serving) or added sugars (more than five grams added sugars per two-tablespoon serving). Better yet, keep it simple and make your own vinaigrette using 2-3 parts oil to 1 part vinegar.</p> <p><strong>Select less salty soup</strong></p> <p><span style="text-decoration: underline;"><em>Instead of:</em></span> one can/carton of vegetable- or bean-based soup</p> <p><span style="text-decoration: underline;"><em>Buy:</em></span> one can/carton of low-sodium vegetable- or bean-based soup</p> <p>When compared to people without diabetes, sodium levels were higher in patients with type 2 diabetes, based on a meta-analysis published in European Journal of Nutrition. Curbing sodium intake is beneficial for people with diabetes since too much may increase your risk for high blood pressure.</p> <p>So, slurp up soup that’s low in sodium. And kick up flavour with a splash of cider vinegar, grated citrus zest, herbs, spices, or a dash of hot sauce.</p> <p><strong>Go for "naked" fish</strong></p> <p><span style="text-decoration: underline;"><em>Instead of:</em></span> Breaded fish sticks</p> <p><span style="text-decoration: underline;"><em>Buy:</em></span> Frozen salmon fillets</p> <p>Cut salmon into large cubes, season, and grill on skewers. Or make fish sticks by simply cutting into skinny fillets, season and roast. Why? Research published in Diabetes Care finds that eating oily fish may be associated with a lower risk of type 2 diabetes. Non-oily fish, like the whitefish in fish sticks, didn’t show this link.</p> <p>Salmon is an oily fish and a major source of omega-3 fatty acids, a heart-friendly fat. Plus: when you make your own salmon skewers or sticks, you won’t have extra carbs from breading.</p> <p><strong>Do dip with a punch of protein</strong></p> <p><span style="text-decoration: underline;"><em>Instead of:</em></span> one container of sour cream &amp; onion dip</p> <p><span style="text-decoration: underline;"><em>Buy:</em></span> one container of pulse-based dip, like hummus</p> <p>Wise snacking can be helpful for managing blood glucose. It can also be delicious. Dunk veggies or wholegrain pita wedges into pulse-based dip, like hummus, black bean dip, or lentil dip. </p> <p>Check this out: one-quarter cup (that’s 60 grams) of onion dip has 870 kiljoules, five grams of saturated fat, 1.2 grams of protein, and 0.1 grams of fibre, while one-quarter cup hummus has 590 kilojoules, 1.5 grams of saturated fat, 4.7 grams of protein, and 3.3 grams of fibre. Hummus clearly wins!</p> <p><em>Image credits: Getty Images</em></p> <p><em>This article originally appeared on <a href="https://www.readersdigest.co.nz/healthsmart/diabetes/reverse-diabetes-10-smart-grocery-swaps?pages=1" target="_blank" rel="noopener">Reader's Digest</a>. </em></p> </div>

Food & Wine

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What is ‘reverse racism’ – and what’s wrong with the term?

<p><a href="https://theconversation.com/profiles/mario-peucker-192086">Mario Peucker</a>, <em><a href="https://theconversation.com/institutions/victoria-university-1175">Victoria University</a></em></p> <p>“Reverse racism” is sometimes used to describe situations where white people believe they are negatively stereotyped or discriminated against because of their whiteness – or treated less favourably than people of colour.</p> <p>“Reverse racism” claims have surfaced in the current debate around the <a href="https://theconversation.com/10-questions-about-the-voice-to-parliament-answered-by-the-experts-207014">Voice to Parliament</a> referendum. “The concept looks racist to me,” <a href="https://www.skynews.com.au/opinion/building-a-voice-to-parliament-into-our-constitution-would-divide-us-along-racial-lines-and-do-nothing-to-change-the-past/news-story/794a86f16d664e6a4ebfbed589b27a01">wrote Sky News commentator Kel Richards</a> last August.</p> <p>Such views misrepresent the Voice as preferential treatment of First Nations peoples, falsely suggesting it would somehow weaken the political say of non-Indigenous Australians.</p> <p>Complaints of reverse racism can be found in the community more generally, too. “I think average, working-class, white Australian males have it the hardest out of anyone in society,” said one 23-year-old man in a <a href="https://www.mdpi.com/2673-995X/3/1/19">2023 study</a> of Australian men, “we are the victims of reverse racism”.</p> <p>“Reverse racism” is an idea that focuses on prejudiced attitudes towards a certain (racialised) group, or unequal personal treatment – namely, discrimination. But it ignores one of racism’s central markers: power.</p> <p>“Prejudice plus (institutional) power” is the widely accepted basic definition of racism. Or, as <a href="https://psycnet.apa.org/record/1998-07453-002">two researchers defined it</a> in 1988: “Racism equals power plus prejudice.”</p> <p>In a <a href="https://www.theguardian.com/stage/2014/jun/04/aamer-rahman-reverse-racism-comedy-tour">famous 2013 sketch</a>, comedian Ahmer Rahman said, yes, reverse racism is possible … if you go back in a time machine and convince the leaders of Africa, Asia and the Middle East to invade and dominate Europe hundreds of years ago, leading to systemic inequality across every facet of social and economic life, “so all their descendants would want to migrate [to] where black and brown people come from”.</p> <p>Put simply, the concept of “reverse racism” – or “anti-white racism” – just doesn’t work, because racism is more than just prejudice.</p> <figure><iframe src="https://www.youtube.com/embed/dw_mRaIHb-M?wmode=transparent&amp;start=0" width="440" height="260" frameborder="0" allowfullscreen="allowfullscreen"></iframe><figcaption><span class="caption">Comedian Ahmer Rahman unpacks ‘reverse racism’, and why making it real would need a time machine.</span></figcaption></figure> <h2>Why ‘reverse racism’ is a myth</h2> <p>Prejudice and discrimination are inherently tied to historically rooted and entrenched, institutionalised forms of systemic racism and racial hierarchies, injustices and power imbalance.</p> <p>The continuing lack of diverse representation in <a href="https://www.theguardian.com/australia-news/2022/jul/25/the-47th-parliament-is-the-most-diverse-ever-but-still-doesnt-reflect-australia">political</a>, social and economic positions of influence is just one of many indicators that we’re still a long way from living in a post-racial society.</p> <p>White people may be called a derogatory name with a reference to their whiteness. They may be discriminated against: for example, by an ethnic business owner who prefers to employ someone from their community background.</p> <p>This may sometimes be unlawful. At other times, it may be a lawful form of “positive action” or “affirmative action”, aimed at reducing historically entrenched, intergenerational and systemic inequalities.</p> <p>But in all these instances – and regardless of whether it’s lawful or not – the term racism, or “reverse racism”, would not apply.</p> <h2>How common are reverse racism claims?</h2> <p>A representative US survey, conducted by PEW in <a href="https://www.pewresearch.org/social-trends/2019/04/09/race-in-america-2019/">2019</a>, found that around 12% of respondents believed “being white hurts people’s ability to get ahead in the country nowadays”. Among white Republicans, the proportion was 22%. It was only 3% among white Democrats.</p> <p>A more recent US survey, in <a href="https://theconversation.com/poll-reveals-white-americans-see-an-increase-in-discrimination-against-other-white-people-and-less-against-other-racial-groups-185278">2022</a>, concluded that 30% of white respondents saw “a lot more discrimination against white Americans”.</p> <p>Representative data on these issues is lacking in Australia. But there is evidence a significant minority of Australians seem convinced anti-white racism is a thing.</p> <p>A 2018 <a href="https://opus.lib.uts.edu.au/bitstream/10453/128799/4/Reverse%20racism%20and%20white%20victimhood%20in%20Australia%20JIS%20March%202018%20clean.pdf">Australian survey</a> found that around 10% of respondents who stated they had witnessed racism as bystanders said the victim of the allegedly “racist” incident was a white person.</p> <p>Another recent (non-representative) <a href="https://periscopekasaustralia.com.au/papers/volume-10-2-2023/demarcating-australias-far-right-political-fringe-but-social-mainstream/">survey</a> of 335 Australian men in 2021 showed that one in three respondents agreed with the statement: “white people are the victims these days”.</p> <p>Australian senator <a href="https://theconversation.com/pauline-hanson-built-a-political-career-on-white-victimhood-and-brought-far-right-rhetoric-to-the-mainstream-134661">Pauline Hanson</a> has been complaining about “reverse racism” since her maiden speech to parliament in 1996, when she described “the privileges Aboriginals enjoy over other Australians”. <a href="https://www.smh.com.au/politics/federal/pauline-hansons-1996-maiden-speech-to-parliament-full-transcript-20160915-grgjv3.html">She said</a>: "We now have a situation where a type of reverse racism is applied to mainstream Australians by those who promote political correctness […]"</p> <p>Gamilaraay man <a href="https://www.theguardian.com/australia-news/commentisfree/2020/mar/12/its-time-to-put-an-end-to-the-gaslighting-that-occurs-every-day-in-australia">Joshua Waters says</a> most First Nations Australians have heard this kind of sentiment, and statements like: “Uh, I’m not racist. You’re racist for calling me racist. Actually, that’s reverse racism!”</p> <p>But as he has argued, “To be called racist for identifying actual racist behaviours and rhetoric is not OK.”</p> <h2>Backlash against racial justice</h2> <p>“Reverse racism” sometimes reflects a naïve but profound lack of racial literacy. But more often, it’s a defensive backlash against societal reckoning with racial injustices, both past and present.</p> <p>And it’s often an expression of “<a href="https://libjournal.uncg.edu/ijcp/article/viewFile/249/116">white fragility</a>” in the face of an <a href="https://scanloninstitute.org.au/mapping-social-cohesion-2022">increasing awareness</a> of racism in Australia – as epitomised by Hanson’s political career.</p> <p>“Reverse racism” claims are often strategically adopted by right-wing populist political actors and far-right fringe movements, to garner support and recruit new sympathisers and members. This can manifest in political stunts such as the infamous “<a href="https://edition.cnn.com/2018/10/15/australia/pauline-hanson-white-australia-intl/index.html">ok to be white</a>” motion Hanson put to the Australian Senate in 2018, which claimed to condemn alleged “anti-white racism”.</p> <p>The phrase “it’s OK to be white” had <a href="https://www.abc.net.au/news/2018-10-17/origins-of-its-ok-to-be-white-slogan-supremacists-united-states/10385716">previously been used</a> by white supremacists in the US.</p> <p>Anti-white racism claims have also been expressed in more explicit, aggressive and extreme ways: as threats of “<a href="https://theconversation.com/how-believers-in-white-genocide-are-spreading-their-hate-filled-message-in-australia-106605">white genocide</a>”, a core neo-Nazi belief.</p> <p>In far-right extremist movements, in Australia and globally, these conspiratorial narratives are commonly used to mobilise – and in some cases, have become crucial drivers for – white supremacy terror attacks, like the 2019 Christchurch mosque shootings in New Zealand, which killed 51 people and injured 49.</p> <p>“Reverse racism” is a skewed, reductionist and ultimately inaccurate understanding of racism.<!-- Below is The Conversation's page counter tag. 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More info: https://theconversation.com/republishing-guidelines --></p> <p><em><a href="https://theconversation.com/profiles/mario-peucker-192086">Mario Peucker</a>, Associate Professor and Principal Research Fellow, <a href="https://theconversation.com/institutions/victoria-university-1175">Victoria University</a></em></p> <p><em>Image credits: Getty Images</em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/what-is-reverse-racism-and-whats-wrong-with-the-term-208009">original article</a>.</em></p>

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No, you can’t reverse ageing by injecting ‘young blood’ and fasting. But that doesn’t stop people trying

<p><a href="https://theconversation.com/profiles/rachael-jefferson-buchanan-297850">Rachael Jefferson-Buchanan</a>, <em><a href="https://theconversation.com/institutions/charles-sturt-university-849">Charles Sturt University</a></em></p> <p>Like many celebrities and entrepreneurs, 45-year-old US tech billionaire Bryan Johnson is <a href="https://www.smh.com.au/lifestyle/health-and-wellness/taking-the-blood-of-your-17-year-old-son-anti-ageing-has-gone-too-far-20230530-p5dcd6.html">trying to reverse the ageing process</a>.</p> <p>Spending an average of US$2 million a year on an anti-ageing regimen, Johnson <a href="https://medium.com/future-literacy/at-45-i-now-age-slower-than-the-average-10-year-old-6932448fc608">claims</a> he now ages slower than some children. He explains: “the pace my body accumulates ageing damage is less than the average ten year old”.</p> <p>Many of Johnson’s age-reversal methods are questionable, involve dodgy science, and have known side effects.</p> <p>While you can’t stop the ageing process, and the gradual decline our bodies experience as we advance in years, there are some things we can all do – for free – to maintain our health as we age.</p> <h2>What does Johnson do? And is it scientific?</h2> <p><strong>Fasting</strong></p> <p>Johnson reports fasting for 23 hours a day. He then eats <a href="https://medium.com/future-literacy/one-meal-23-hr-fast-100-nutrition-18187a2f5b">one meal a day</a>: 2,250 calories of nutrient-dense food “customised” to his body’s needs.</p> <p>Eating for time-restricted periods in the day can have a <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9650338/">positive effect</a> on how we <a href="https://pubmed.ncbi.nlm.nih.gov/29955217/">metabolise nutrients</a>, inflammation levels, hormonal regulation, and <a href="https://www.health.harvard.edu/blog/how-good-is-your-cardiometabolic-health-and-what-is-that-anyway-202208182803">cardiometabolic health</a> (blood sugar, <a href="https://www.mayoclinic.org/diseases-conditions/high-blood-cholesterol/in-depth/triglycerides/art-20048186">triglycerides</a>, cholesterol, blood pressure, BMI and waist circumference).</p> <p>However, a Spartan-like food intake can <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121099/">impair</a> how our body responds to sugar (known as glucose tolerance). And it’s not necessarily any more effective for weight maintenance than <a href="https://pubmed.ncbi.nlm.nih.gov/29419624/">reducing calorie intake at each meal</a>.</p> <p>Large-scale, long-term human trials are needed to confirm the <a href="https://pubmed.ncbi.nlm.nih.gov/34728336/">limited risk-benefit</a> findings of fasting.</p> <p><strong>Acid peels</strong></p> <p>Johnson has weekly <a href="https://www.asds.net/skin-experts/skin-treatments/chemical-peels/chemical-peels-for-aging-skin">acid peels</a> (which use a mild acid to exfoliate the skin) to maintain a “youthful glow”.</p> <p>But you cannot smooth sagging facial skin or remove deep scars or wrinkles. Acid peels also <a href="https://www.mayoclinic.org/tests-procedures/chemical-peel/about/pac-20393473">come with risks</a>, including organ damage, infection, scarring and swelling.</p> <p><strong>Plasma infusions</strong></p> <p>Perhaps the most bizarre youth-inducing procedure Johnson has attempted is receiving blood transfusions from his 17-year-old son.</p> <p>US biotech companies have explored <a href="https://www.theguardian.com/society/2020/feb/02/could-young-blood-stop-us-getting-old-transfusions-experiments-mice-plasma">plasma infusions</a> to tackle age-related diseases in humans for decades. But there are no proven clinical benefits.</p> <p><a href="https://www.redcrossblood.org/donate-blood/blood-donation-process/what-happens-to-donated-blood/blood-transfusions/risks-complications.html">Side effects from blood transfusions</a> include blood-borne infections, fever and allergic reactions.</p> <h2>Historical attempts to stay youthful</h2> <p>Humans have been experimenting with <a href="https://academic.oup.com/biomedgerontology/article/59/6/B515/662071">anti-ageing methods for centuries</a>. These have included all sorts of behavioural and lifestyle practices that are quirky, questionable, and even sadistic.</p> <p>Ancient practices included <a href="https://www.marieclaire.com/beauty/news/a14382/anti-aging-beauty-through-history/">crocodile dung face masks</a>, which the Greeks and Romans used to brighten their complexions.</p> <p>Romans also used <a href="https://beautytap.com/2019/03/donkey-milk">donkey milk</a> and <a href="https://www.ancient-origins.net/history/swans-fat-crocodile-dung-and-ashes-snails-achieving-beauty-ancient-rome-003240">swan fat</a> to minimise wrinkles, due to their acclaimed rejuvenating properties.</p> <p><a href="https://www.livescience.com/44071-cleopatra-biography.html">Cleopatra</a> apparently took daily baths in sour donkey milk. To sustain this lavish habit, she had a <a href="https://www.naturanecosmetics.com/en/content/26-faits-historiques">herd of 700 donkeys</a>. Sour milk contains <a href="https://science.jrank.org/pages/3780/Lactic-Acid-Lactic-acid-in-foods.html">lactic acid</a>, a naturally occurring <a href="https://www.mecca.com.au/edits/ingredients/alpha-hydroxy-acids/">alpha-hydroxy acid (AHA)</a> that exists in many modern-day exfoliants. So this idea was grounded in basic science, at least.</p> <figure class="align-center "><img src="https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px" srcset="https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=600&amp;h=400&amp;fit=crop&amp;dpr=1 600w, https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&amp;q=30&amp;auto=format&amp;w=600&amp;h=400&amp;fit=crop&amp;dpr=2 1200w, https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&amp;q=15&amp;auto=format&amp;w=600&amp;h=400&amp;fit=crop&amp;dpr=3 1800w, https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;h=503&amp;fit=crop&amp;dpr=1 754w, https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&amp;q=30&amp;auto=format&amp;w=754&amp;h=503&amp;fit=crop&amp;dpr=2 1508w, https://images.theconversation.com/files/530478/original/file-20230607-27-bv0w1t.jpg?ixlib=rb-1.1.0&amp;q=15&amp;auto=format&amp;w=754&amp;h=503&amp;fit=crop&amp;dpr=3 2262w" alt="Milk bath with dried fruits and flowers" /><figcaption><span class="caption">Don’t waste milk on a bath.</span> <span class="attribution"><a class="source" href="https://www.shutterstock.com/image-photo/bath-milk-flowers-1051210370">Shutterstock</a></span></figcaption></figure> <p>During the 16th and 17th century, “Countess Dracula” aka <a href="https://en.wikipedia.org/wiki/Elizabeth_B%C3%A1thory">Elizabeth Bathory</a> allegedly resorted to serial killing to quench her thirst for youthfulness, <a href="https://www.nationalgeographic.com/travel/article/the-bloody-legend-of-hungarys-serial-killer-countess">bathing in the blood of her young victims</a>.</p> <h2>The quest continues with cryotherapy</h2> <p>Fountain of youth fixations have inspired many contemporary anti-ageing trends. Exposure to cold is a firm favourite.</p> <p><a href="https://www.nature.com/articles/s43587-023-00383-4">Some research</a> suggests this could have <a href="https://neurosciencenews.com/cold-aging-22928/">benefits</a> relating to longevity, by slowing cellular degeneration, <a href="https://www.cryo.com.au/anti-ageing-benefits-of-whole-body-cryotherapy/">stimulating collagen and elastin production</a>, increasing the metabolism, and reducing inflammation.</p> <p>Dutch motivational speaker Wim Hof includes <a href="https://www.wimhofmethod.com/cold-water-immersion">cold water immersion</a> as one of the three pillars of his <a href="https://www.wimhofmethod.com/">Wim Hof Method</a> to “increase mind-body connection”.</p> <p>Athletes such as <a href="https://www.dailymail.co.uk/sport/football/article-2469985/Cristiano-Ronaldo-buys-Cryotherapy-chamber.html">Cristiano Ronaldo</a> use <a href="https://my.clevelandclinic.org/health/treatments/21099-cryotherapy">cryotherapy</a>, exposing their bodies to extremely cold temperatures for two to four minutes to decrease the signs of ageing and enhance their general health.</p> <p>However, the <a href="https://www.medicinenet.com/what_are_the_side_effects_of_cryotherapy/article.htm">risks of cryotherapy</a> include bone fractures, frostbite, nerve damage, bleeding, cramping, swelling and skin infections.</p> <h2>So what can we do to age well?</h2> <p>Two of the more mainstream anti-ageing methods that Johnson recommends are the daily self-care habits of sleep and exercise.</p> <p>He has a <a href="https://medium.com/future-literacy/sleep-and-impulse-control-87e844218ff2">strict sleep schedule</a> that involves retiring to bed at 8pm, with a one-hour wind-down in a darkened room.</p> <p>Adults report poorer sleep quality and difficulty being able to sleep for long enough <a href="https://www.news-medical.net/health/How-Does-the-Suprachiasmatic-Nucleus-(SCN)-Control-Circadian-Rhythm.aspx">as they age</a>. Sleeping too much or too little is <a href="https://www.frontiersin.org/articles/10.3389/fpubh.2023.1043347/full">associated with</a> a greater risk of obesity, heart disease and <a href="https://theconversation.com/research-check-can-sleeping-too-much-lead-to-an-early-death-101323">premature death</a>.</p> <p>Developing a regular sleep routine, reducing bedroom distractions such as mobile phones, and exercising regularly can all help to <a href="https://www.sleepfoundation.org/aging-and-sleep">alleviate sleep problems</a>.</p> <figure class="align-center "><img src="https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip" sizes="(min-width: 1466px) 754px, (max-width: 599px) 100vw, (min-width: 600px) 600px, 237px" srcset="https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=600&amp;h=383&amp;fit=crop&amp;dpr=1 600w, https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&amp;q=30&amp;auto=format&amp;w=600&amp;h=383&amp;fit=crop&amp;dpr=2 1200w, https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&amp;q=15&amp;auto=format&amp;w=600&amp;h=383&amp;fit=crop&amp;dpr=3 1800w, https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;h=482&amp;fit=crop&amp;dpr=1 754w, https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&amp;q=30&amp;auto=format&amp;w=754&amp;h=482&amp;fit=crop&amp;dpr=2 1508w, https://images.theconversation.com/files/530491/original/file-20230607-29-cw0f29.jpg?ixlib=rb-1.1.0&amp;q=15&amp;auto=format&amp;w=754&amp;h=482&amp;fit=crop&amp;dpr=3 2262w" alt="Child and grandfather walk on a beach" /><figcaption><span class="caption">Exercise is also important for healthy ageing.</span> <span class="attribution"><a class="source" href="https://unsplash.com/photos/s-vhziQHngM">Vidar Nordi Mathisen/Unsplash</a></span></figcaption></figure> <p>Exercise, often cited as a <a href="https://www.marketwatch.com/story/exercise-is-the-wonder-drug-for-healthy-aging-11633642719">wonder drug for healthy ageing</a>, is something Johnson takes very seriously. He does a “<a href="https://www.youtube.com/watch?v=HNywRJgCRaQ">Blueprint</a>” workout that includes specially designed daily techniques, as well as <a href="https://www.hsph.harvard.edu/nutritionsource/high-intensity-interval-training/">high-intensity interval training sessions</a>, hiking and playing sport.</p> <p>From middle age onwards, we all need to exercise regularly, to increase our muscle mass, bone density, strength, endurance, coordination and balance. One of the greatest health risks for older people is <a href="https://www.ncbi.nlm.nih.gov/books/NBK560761/">falling</a>, which balance, flexibility, endurance and strength training <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC381224/">can help</a> reduce. Physical activity can bring <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5408452/">social benefits</a> in older adults if undertaken in groups, and there are well-known <a href="https://www.whiddon.com.au/yourlife/the-mental-health-benefits-of-exercise-for-older-adults/">mental health gains</a>.</p> <p>Small changes in sleep, diet (eating <a href="https://health.gov/news/202107/nutrition-we-age-healthy-eating-dietary-guidelines">plenty of vegetables, fruit, wholegrains, healthy fats, and enough protein</a>), and exercise can support <a href="https://bmcgeriatr.biomedcentral.com/articles/10.1186/s12877-020-01900-5">healthy ageing</a>, reducing the chance of early death, and helping us all to lead an active and independent life in our senior years. Now that <em>is</em> something worth investing in.<img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important;" src="https://counter.theconversation.com/content/207038/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /></p> <p><a href="https://theconversation.com/profiles/rachael-jefferson-buchanan-297850">Rachael Jefferson-Buchanan</a>, Lecturer in Human Movement Studies (Health and PE) and Creative Arts, <em><a href="https://theconversation.com/institutions/charles-sturt-university-849">Charles Sturt University</a></em></p> <p><em>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/no-you-cant-reverse-ageing-by-injecting-young-blood-and-fasting-but-that-doesnt-stop-people-trying-207038">original article</a>.</em></p> <p><em>Images: Getty</em></p>

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“Benjamin Button” mice could pave way for reverse ageing

<p>If the three blind mice from the iconic nursery rhyme were living in molecular biologist Dr David Sinclair’s lab at Harvard Medical School, they might not be blind for very long.</p> <p>Dr Sinclair and his team at Harvard Medical School have been using proteins that can turn adult cells into stem cells - a kind of cell that can be turned into any of the specialised cells our bodies need.</p> <p>These stem cells have been helping restore the sight of old mice with damaged retinas, essentially making them younger versions of themselves.</p> <p>“It’s a permanent reset, as far as we can tell, and we think it may be a universal process that could be applied across the body to reset our age,” Dr Sinclair said about his research, which was published in late 2020.</p> <p>The Australian scientist has spent the past 20 years studying ways to reverse the effects of ageing - including the diseases that can afflict us as we get older.</p> <p>“If we reverse ageing, these diseases should not happen,” he said.</p> <p>During a health and wellness talk at Life Itself, Dr Sinclair said the technology is available and it’s only a matter of when we decide to use it.</p> <p>“We have the technology today to be able to go into your hundreds without worrying about getting cancer in your 70s, heart disease in your 80s and Alzheimer’s in your 90s,” he said.</p> <p>“This is the world that is coming. It’s literally a question of when and for most of us, it’s going to happen in our lifetime.”</p> <p>Whitney Casey, an investor who has partnered with Dr Sinclair to create a DIY biological age test, said the researcher wants to “make ageing a disease”.</p> <p>“His research shows you can change ageing to make lives younger for longer,” she said.</p> <p>Dr Sinclair said that when it comes to how modern medicine addresses sickness, it doesn’t tackle the underlying cause, which is usually “ageing itself”.</p> <p>“We know that when we reverse the age of an organ like the brain in a mouse, the diseases of ageing then go away. Memory comes back, there is no more dementia,” he continued.</p> <p>“I believe that in the future, delaying and reversing ageing will be the best way to treat the diseases that plague most of us.”</p> <p>Dr Sinclair’s research comes amid a global effort by scientists working to reprogram adult cells into stem cells, started by Japanese researcher Shinya Yamanaka, who won a Nobel Prize for reprogramming adult skin cells into behaving like embryonic (or pluripotent) stem cells.</p> <p>These “induced pluripotent stem cells” became known as “Yamanaka factors”, with later research finding that exposing cells to four of the main Yamanaka factors could remove signs of ageing.</p> <p>Since their original study, where they discovered that damaged cells were able to be rejuvenated by injecting three of these factors into the eyes of mice, Dr Sinclair and his lab have reversed ageing in mouse brains and muscles, and are now working on a mouse’s whole body.</p> <p>Dr Sinclair said their discovery indicated that there is a “back-up copy” of youthful information stored in the body, which he calls the “information theory of ageing”.</p> <p>“It’s a loss of information that drives ageing cells to forget how to function, to forget what type of cell they are,” he revealed.</p> <p>“And now we can tap into a reset switch that restores the cell’s ability to read the genome correctly again, as if it was young.”</p> <p><em>Image: Getty Images</em></p>

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Genetic discovery may help scientists reverse hearing loss

<p>Neuroscience researchers have found a master gene that controls the development of special sensory cells in the ears – potentially opening the door to reversing hearing loss.</p> <p>A team led by Jaime García-Añoveros of Northwestern University, US, established that a gene called Tbx2 controls the development of ear hair cells in mice. The findings of their study are <a href="https://www.nature.com/articles/s41586-022-04668-3" target="_blank" rel="noreferrer noopener">published today in <em>Nature</em></a><em>.</em></p> <p><strong>What are hair cells?</strong></p> <p>Hair cells are the sensory cells in our ears that detect sound and then transmit a message to our brains. They are so named because they have tiny hairlike structures called stereocilia.</p> <p>“The ear is a beautiful organ,” says García-Añoveros. “There is no other organ in a mammal where the cells are so precisely positioned.”</p> <p>Hair cells are found in a structure called the organ of Corti, in the cochlea in the inner ear. The organ of Corti sits on top of the basilar membrane.</p> <p>Sound waves are funnelled through our ear canal and cause the eardrum (also known as the tympanic membrane) and ossicles (tiny bones called the malleus, incus and stapes) to vibrate. The vibrations, or waves, are transmitted through fluid in the cochlea, causing the basilar membrane to move as well.</p> <p>When the basilar membrane moves, the stereocilia tilt, causing ion channels in the hair cell membrane to open. This stimulates the hair cell to release neurotransmitter chemicals, which will transmit the sound signal to the brain via the auditory nerve.</p> <figure class="wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio"> <div class="wp-block-embed__wrapper"> <div class="entry-content-asset"> <div class="embed-wrapper"> <div class="inner"><iframe title="2-Minute Neuroscience: The Cochlea" src="https://www.youtube.com/embed/WeQluId1hnQ?feature=oembed" width="500" height="281" frameborder="0" allowfullscreen="allowfullscreen"></iframe></div> </div> </div> </div> </figure> <h2> </h2> <p><strong>Hair cells and hearing loss</strong></p> <p>There are actually two types of hair cells: inner and outer. We need both types to hear effectively. The outer hair cells change their shape and amplify sound for the inner hair cells, which transmit the vibrations to the brain.</p> <div class="newsletter-box"> <div id="wpcf7-f6-p190195-o1" class="wpcf7" dir="ltr" lang="en-US" role="form"> <form class="wpcf7-form mailchimp-ext-0.5.61 init" action="/science/genetic-discovery-reverse-hearing-loss/#wpcf7-f6-p190195-o1" method="post" novalidate="novalidate" data-status="init"> <p style="display: none !important;"><span class="wpcf7-form-control-wrap referer-page"><input class="wpcf7-form-control wpcf7-text referer-page" name="referer-page" type="hidden" value="https://cosmosmagazine.com/health/" data-value="https://cosmosmagazine.com/health/" aria-invalid="false" /></span></p> <p><!-- Chimpmail extension by Renzo Johnson --></form> </div> </div> <p>“It’s like a ballet,” says García-Añoveros. “The outers crouch and jump and lift the inners further into the ear.”</p> <p>Hair cells develop before we are born and do not typically divide to create new versions of themselves. As we age, our hair cells die, <a href="https://cosmosmagazine.com/health/hair-cell-loss-may-explain-hearing-loss/">leading to hearing loss</a>. Loss of outer hair cells is particularly common.</p> <p>According to the US Centers for Disease Control, about 8.5% of adults aged 55-64 in the US experience “disabling” hearing loss, with that number increasing to nearly 25% in people aged 65-74, and 50% in those 75 and older.</p> <p><strong>Could we one day reverse hearing loss?</strong></p> <p>Since hair cells don’t usually divide, we may be able to reverse hearing loss if we can reprogram stem cells or other cells in the ear to become hair cells to replace those that die.</p> <p>Scientists have already produced artificial hair cells, but until now didn’t know how to direct the cell to become an inner or an outer hair cell.</p> <p>The team at Northwestern discovered that a gene called Tbx2 controls the development of both inner and outer hair cells. If Tbx2 is “switched on” to produce the protein TBX2, the cell develops into an inner hair cell. If Tbx2 is “off”, it becomes an outer hair cell.</p> <p>“Our finding gives us the first clear cell switch to make one type versus the other,” García-Añoveros explains.</p> <p>The finding is a step towards learning how we can reprogram the cells that usually provide structural support for the hair cells to become inner or outer hair cells themselves – replacing dead hair cells and preventing or reversing hearing loss.</p> <p>“We can now figure out how to make specifically inner or outer hair cells and identify why the latter are more prone to dying,” García-Añoveros says. “We have overcome a major hurdle.”</p> <p><!-- Start of tracking content syndication. Please do not remove this section as it allows us to keep track of republished articles --></p> <p><img id="cosmos-post-tracker" style="opacity: 0; height: 1px!important; width: 1px!important; border: 0!important; position: absolute!important; z-index: -1!important;" src="https://syndication.cosmosmagazine.com/?id=190195&amp;title=Genetic+discovery+may+help+scientists+reverse+hearing+loss" width="1" height="1" data-spai-target="src" data-spai-orig="" data-spai-exclude="nocdn" /></p> <p><!-- End of tracking content syndication --></p> <div id="contributors"> <p><em><a href="https://cosmosmagazine.com/science/genetic-discovery-reverse-hearing-loss/" target="_blank" rel="noopener">This article</a> was originally published on <a href="https://cosmosmagazine.com" target="_blank" rel="noopener">Cosmos Magazine</a> and was written by <a href="https://cosmosmagazine.com/contributor/matilda-handlsey-davis" target="_blank" rel="noopener">Matilda Handsley-Davis</a>. Matilda is a science writer at Cosmos. She holds a Bachelor of Arts and a Bachelor of Science (Honours) from the University of Adelaide.</em></p> <p><em>Image: Getty Images</em></p> </div>

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That reverse mortgage scheme the government is about to re-announce, how does it work?

<p>Many Australians have never heard of the <a href="https://www.servicesaustralia.gov.au/pension-loans-scheme">Pension Loans Scheme</a>, and many more assume it’s just for pensioners, which is understandable given its name.</p> <p>That’s why the government is poised to rename it the Home Equity Access Scheme and make the interest rate it charges more reasonable, in the mid-year budget update on Thursday.</p> <p>The soon to be renamed scheme is best thought of as a <a href="https://www.investopedia.com/mortgage/reverse-mortgage/">reverse mortgage</a> where instead of paying down a home loan each month, the homeowner borrows more against the home each month, paying off what’s borrowed when the home is eventually sold.</p> <p>Although reverse mortgages have been provided commercially for some time, the number of providers has shrunk as large banks have <a href="https://download.asic.gov.au/media/4851420/rep-586-published-28-august-2018.pdf">left the field</a> in the face of increased scrutiny and compliance costs.</p> <p>The government version is misleadingly named the Pension Loans Scheme (PLS), even though it is available to all retirees with homes and not just pensioners. It was introduced by the Hawke government in <a href="https://www.aph.gov.au/About_Parliament/Parliamentary_Departments/Parliamentary_Library/FlagPost/2015/February/The_Pension_Loans_Scheme">1985</a>.</p> <p>The maximum amount that can be made available under the scheme and the age pension combined is <a href="https://www.servicesaustralia.gov.au/how-much-you-can-get-under-pension-loans-scheme?context=22546">150% of the full pension.</a> This means a retiree who is on the pension can get extra fortnightly payments from the scheme to bring their total payment up to 150% of the full pension.</p> <p>If the retiree is not on the pension they can get the entire amount of 150% of the pension via the PLS.</p> <p>The payments stop when the loan balance reaches a <a href="https://www.servicesaustralia.gov.au/maximum-loan-amount-under-pension-loans-scheme?context=22546">ceiling</a> which climbs each year the retiree gets older and climbs with increases in the value of the home.</p> <p>The ceiling for a 70-year old with a home worth $1,000,000 is $308,000.</p> <p>The key difference between the PLS and commercial reverse mortgages is that the size of its lump sum payments is limited. Payments under the PLS have no impact on the pension, whereas commercial reverse mortgages can trigger the means test.</p> <p><a href="https://images.theconversation.com/files/437703/original/file-20211215-13-kxrv2s.png?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=1000&amp;fit=clip"><img src="https://images.theconversation.com/files/437703/original/file-20211215-13-kxrv2s.png?ixlib=rb-1.1.0&amp;q=45&amp;auto=format&amp;w=754&amp;fit=clip" alt="" /></a> <span class="caption"></span> <span class="attribution"><span class="source">Colin Zhang, Macquarie Business School</span></span></p> <p>As attractive as the PLS might appear, hardly any of the four million or so Australians aged 65 and over have taken it up, perhaps as few as <a href="https://newsroom.unsw.edu.au/news/business-law/budget-changes-make-pension-loans-scheme-more-attractive-senior-homeowners">5,000</a> – one in every 800.</p> <p>So in this year’s May budget the government announced two changes to make it more attractive.</p> <p>One was a “<a href="https://cdn.theconversation.com/static_files/files/1902/PLS_2021-22-budget-16_%281%29.pdf">no negative equity guarantee</a>”. Users would never be asked repay more than the value of their property, even if the property fell in value.</p> <p>The other was the ability to take out up to <a href="https://cdn.theconversation.com/static_files/files/1902/PLS_2021-22-budget-16_%281%29.pdf">two lump sums per year</a> totalling up to 50% of the full pension in addition to fortnightly payments.</p> <p>Total government payments would remain capped at 150% of the pension.</p> <h2>New brand, same scheme</h2> <p>That second change won’t begin until July 1, 2022 and is likely to be re-announced in Thursday’s mid-year budget update.</p> <p>Also announced in the budget was a decision to raise awareness of the scheme “through improved public messaging and branding” something which is also likely to be re-announced on Thursday along with the new name.</p> <p>The other change expected on Thursday is a lower interest rate charged on the sums borrowed. In January 2020, the rate was cut from 5.25% to 4.5% in accordance with cuts in other rates. From January next year it should reduce further to <a href="https://www.theaustralian.com.au/nation/politics/scott-morrison-opens-up-mortgage-loan-scheme-to-help-elderly-fund-their-own-retirements/news-story/9f8c56fbba899f6b76c72ce51ceb9331">3.95%</a>.</p> <h2>Attractive, but not riskless</h2> <p>There remain risks associated with taking advantage of the scheme.</p> <p>One is that if you live long enough you are likely to eventually hit the ceiling and be unable to take out any more money, suffering a loss of income.</p> <p>If you chose to sell your home and move to an aged care service, you need to use a big part of your sale proceedings to pay what’s owed.</p> <p>Other risks are that neither the interest rate nor home prices are fixed.</p> <p>Just as the government has cut the rate charged in line with cuts to lower general interest rates, it might well lift it when interest rates climb. And home prices can go down as well as up, meaning that, at worst, all of the value of your home (although no more) can be gobbled up in repayments.<!-- Below is The Conversation's page counter tag. Please DO NOT REMOVE. --><img style="border: none !important; box-shadow: none !important; margin: 0 !important; max-height: 1px !important; max-width: 1px !important; min-height: 1px !important; min-width: 1px !important; opacity: 0 !important; outline: none !important; padding: 0 !important; text-shadow: none !important;" src="https://counter.theconversation.com/content/171671/count.gif?distributor=republish-lightbox-basic" alt="The Conversation" width="1" height="1" /><!-- End of code. If you don't see any code above, please get new code from the Advanced tab after you click the republish button. The page counter does not collect any personal data. More info: https://theconversation.com/republishing-guidelines --></p> <p><span><a href="https://theconversation.com/profiles/colin-zhang-1234147">Colin Zhang</a>, Lecturer, Department of Actuarial Studies and Business Analytics, <em><a href="https://theconversation.com/institutions/macquarie-university-1174">Macquarie University</a></em> and <a href="https://theconversation.com/profiles/ning-wang-1297929">Ning Wang</a>, Associate Research Fellow, <em><a href="https://theconversation.com/institutions/university-of-wollongong-711">University of Wollongong</a></em></span></p> <p>This article is republished from <a href="https://theconversation.com">The Conversation</a> under a Creative Commons license. Read the <a href="https://theconversation.com/that-reverse-mortgage-scheme-the-government-is-about-to-re-announce-how-does-it-work-171671">original article</a>.</p> <p><em>Image: Shutterstock</em></p>

Real Estate

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New study reveals how to reverse type 2 diabetes

<p>A new study suggests that type 2 diabetes can be reversed through a short-term low carbohydrate diet.</p> <p>CSIRO conducted research with labs across the world and discovered a dietary pattern that is lower in carbohydrates and higher in protein and healthy fats is actually more effective for improving your blood glucose management.</p> <p>They analysed 23 published clinical trials from around the world, which compared low-carb diets to mostly low-fat control diets.</p> <p>Patients who were careful about the number of carbs they consumed were more likely to drive their diabetes into remission without adverse effects, they were also able to achieve a higher amount of weight loss after six months.</p> <p><img style="width: 500px; height: 280.8417997097242px;" src="https://oversixtydev.blob.core.windows.net/media/7839505/screen-shot-2021-01-15-at-21953-pm.png" alt="" data-udi="umb://media/e3b24e41b7514401b391f40cd308680b" /></p> <p>George Inatey decided to cut out carbohydrates from his diet, and he claims he is now a new man.</p> <p>Within six months the type 2 diabetic went from weighing over 100kg down to 62kg.</p> <p>He also no longer requires several insulin injections a day to control his diabetes.</p> <p>His blood pressure and cholesterol have also improved.</p> <p>"It was the most liberating thing I've done in my life in 40 years," he told 9News.</p> <p>Researchers say most of the benefits went away after 12 months, which could be due to the intensity and challenges of maintaining a strict diet.</p> <p>It's an option people should consider but in consultation with a health professional.</p>

Caring

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Memory loss? Here's how you can reverse it

<p><span style="font-weight: 400;">Memory loss has been a longstanding concern amongst the ageing community. However, two new studies have shown that it is possible to restore working memory and reverse age-related memory impairment.</span></p> <p><span style="font-weight: 400;">The two studies, conducted separately by Boston University and the Northwestern University Feinberg School of Medicine, found that people in their 60s and 70s can boost their brain function through various methods of stimulation.</span></p> <p><span style="font-weight: 400;">Following the experiments, the memory of the older people in both studies was boosted to a level that was indistinguishable from that of younger adults. </span></p> <p><span style="font-weight: 400;">“Older people’s memory got better up to the level that we could no longer tell them apart from younger people,” said Joel Voss, associate professor and lead author of the Northwestern study.</span></p> <p><span style="font-weight: 400;">In the Northwestern research, to be published in the </span><em><a href="https://n.neurology.org/"><span style="font-weight: 400;">Neurology</span></a></em> <span style="font-weight: 400;">journal, 16 people aged 64 to 80 with normal age-related memory problems underwent Transcranial Magnetic Stimulation (TMS). The method was aimed at stimulating the hippocampus, a part of the brain which is involved in the formation of new memories. </span></p> <p><span style="font-weight: 400;">“It’s the part of the brain that links two unrelated things together into a memory, like the place you left your keys or your new neighbour’s name,” said Voss. In older people, the hippocampus tends to atrophy and shrink, resulting in memory decline.</span></p> <p><span style="font-weight: 400;">After the stimulation was applied for 20 minutes a day for five consecutive days, the participants’ performance in memory tasks improved to the level of young adults.</span></p> <p><span style="font-weight: 400;">Meanwhile for the Boston University study published in </span><a href="https://www.nature.com/articles/s41593-019-0371-x"><span style="font-weight: 400;"><em>Nature Neuroscience</em></span></a><span style="font-weight: 400;">, a group of people in their 60s and 70s was tested with a memory game against a group of people in their 20s. </span></p> <p><span style="font-weight: 400;">At baseline, the younger group outperformed the older group significantly – however, after the latter received 25 minutes of mild electro-stimulation tuned to their individual brain circuits, “the difference between the two groups vanished.” The effect lasted at least until the experiment ended, or 50 minutes after the stimulation.</span></p> <p><span style="font-weight: 400;">The benefits of the stimulation are not limited to older people – some younger adults who performed poorly on the game also gained better results after getting the same treatment. </span></p> <p><span style="font-weight: 400;">According to the researchers, this is because the electrical currents helped neural circuits in the brain find their rhythm back and become more coordinated.</span></p> <p><span style="font-weight: 400;">“We showed that the poor performers who were much younger, in their 20s, could also benefit from the same exact kind of stimulation,” said Robert Reinhart, assistant professor of psychological and brain sciences at Boston University and lead author of the study. “We could boost their working memory even though they weren’t in their 60s or 70s.”</span></p> <p><span style="font-weight: 400;">While the results are promising, it is yet to be seen whether these approaches can be applied more widely to help more people with age-related cognitive decline. </span></p>

Mind

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Are your hands ageing you? 3 ways to reverse the clock

<p>As women, we spend an enormous amount of money on lotions and potions that promise to keep the skin on our face looking younger than our years. We hope that these investments will keep others second guessing, as they fight over how old we <em>really</em> are.</p> <p>And while we hear time and time again how important it is to take care of our skin, what we fail to listen to is that this doesn’t just include our face – but our hands as well. The skin on our hands age the fastest and it makes sense as to why.</p> <p>They’re constantly working hard. Whether they’re exposed to the sun for long periods of time, or they’re suffering from the drying affect of dishwashing soap when washing the dishes. And here’s the cold hard truth: The skin on your face can be wrinkle free and devoid of any blemish, but if you fail to take care of your hands, it will give away your age faster than anything else.</p> <p>As we get older, a number of conditions can affect our hands. We experience bruising a lot easier, and the skin becomes thinner, exposing veins we didn’t even know we had.</p> <p>Here are the steps to ensure youthful hands for eternity:</p> <p><strong>1. Moisturise</strong></p> <p>Keep a hydrating hand cream in your hand bag, on your desk, in the car, basically wherever you go, your hand cream goes too. Bonus points if it has wrinkle-fighting ingredients such as retinol or glycolic acid.</p> <p><strong>2. Protect your hands</strong></p> <p>Enjoy gardening? Or maybe you’re constantly standing by the sink washing dishes. Whatever the situation, try and wear gloves if it calls for it. Not only do gloves protect your hands from sun exposure, but also harsh chemicals that we’re regularly exposed to.</p> <p><strong>3. Eat for your skin and nails</strong></p> <p>Beauty starts from within, and while it may sound like a cliché, it’s an important lesson to understand. A diet rich with nutrients will stop the clock faster than expensive skincare. Look for ingredients such as Omega-3s, B vitamins, vitamin C, antioxidants and protein.</p> <p>Do you have any anti-ageing tips you would like to share? Let us know in the comments below.</p>

Beauty & Style

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Eye drops could reverse cataracts

<p>Those who suffer from cataracts will know the frustration that comes from this degenerative eye disease. Cataracts affect more than 20 million people worldwide and are caused when the lenses of the eyes lost their transparency. In exciting eye care news, a team of American researchers believe to have made a breakthrough in the treatment of cataracts, using eye drops to reverse cataracts altogether. Impressive.</p> <p>Researchers from the University of California in San Francisco (UCSF) have identified a new compound that is soluble enough to be administered via a simple eye dropper. What’s more, when tested on mice, results were seen in as little as two weeks.</p> <p>While cataracts are treatable, surgery can be uncomfortable and very expensive. Elderly people in developing nations are also affected by this disease, as many don’t have access to resources to treat it.</p> <p>Jason Gestwicki, associate professor at UCSF, says this finding has the potential to help millions of people, and potential lots of applications. "If you look at… the protein aggregates that cause cataracts, you'd be hard-pressed to tell them apart from those that cause Alzheimer's, Parkinson's, or Huntington's diseases," he said. "By studying cataracts we've been able to… show by proof-of-concept that these technologies could also be used in nervous system diseases.”</p> <p>Imagine treating Alzheimer’s Disease or eye issues with a simple drop. Well, it might not belong in the realm of imagination anymore. </p> <p><strong>Related links:</strong></p> <p><em><span style="text-decoration: underline;"><strong><a href="/health/hearing/2015/12/gene-therapy-breakthrough-hearing-loss/">Gene therapy breakthrough for treatment of hearing loss</a></strong></span></em></p> <p><em><span style="text-decoration: underline;"><strong><a href="/health/eye-care/2015/11/how-often-should-you-get-your-eyes-tested/">How often should you visit your optometrist?</a></strong></span></em></p> <p><em><span style="text-decoration: underline;"><strong><a href="/news/news/2015/11/specsavers-spectacle-style-competition/">83-year-old crowned “Spectacle Wearer of the Year”</a></strong></span></em></p> <p> </p>

Eye Care

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The breakthrough that can reverse sun damage

<div id="yui_3_16_0_1_1447968647113_116431"> <div id="yui_3_16_0_1_1447968647113_116513"><span style="font-family: Calibri, sans-serif;">As a country that loves to be outdoors, it’s no surprise that New Zealand's rate of skin cancer are among the highest in the world.  But, in a landmark Australian study, researchers have found that cutting the melanoma rate could be possible with a simple vitamin.</span></div> <div id="yui_3_16_0_1_1447968647113_116520"><span style="font-family: Calibri, sans-serif;"> </span></div> <div id="yui_3_16_0_1_1447968647113_116509"><span style="font-family: Calibri, sans-serif;">Nicotinamide is a form of vitamin B3 that’s available in supplement form. It works by accelerating the repair of DNA damage caused by harmful UV rays, and in turn reducing the incidence of skin spots. What’s more, it’s inexpensive and readily available at many pharmacies.</span></div> <div id="yui_3_16_0_1_1447968647113_116506"><span style="font-family: Calibri, sans-serif;"> </span></div> <div id="yui_3_16_0_1_1447968647113_116523"><span style="font-family: Calibri, sans-serif;">New research by the University of Sydney has found that when taken as a supplement, this vitamin can lower the risk of developing non-melanoma skin cancer by 23 per cent. The year-long study involved 386 people, who averaged 66 years old and had had two or more skin cancers in the last five years. Those who took 500 milligrams of nicotinamide twice a day experienced the dramatic results.</span></div> <div><span style="font-family: Calibri, sans-serif;"> </span></div> <div id="yui_3_16_0_1_1447968647113_116504"><span style="font-family: Calibri, sans-serif;">Dr Michel Freeman, Principal Dermatologist at The Skin Centre Suite has been prescribing the vitamin for two years and says these new results are in-line with his patient experience. “I’m seeing approximately a one third reduction in sun-related cancers and pre-cancers in my patients when nicotinamide is taken daily,” he told Over60.</span></div> <div id="yui_3_16_0_1_1447968647113_116525"><span style="font-family: Calibri, sans-serif;"> </span></div> <div><span style="font-family: Calibri, sans-serif;">Dr Freeman believes nicotinamide won’t just impact patients, but given this new research should have big implications on the healthcare system. “This could potentially save the health system a significant amount of money,” he says. </span></div> <div><span style="font-family: Calibri, sans-serif;"> </span></div> <div id="yui_3_16_0_1_1447968647113_116548"><span style="font-family: Calibri, sans-serif;">So, is this supplement right for you? Dr Freeman says people with a history of skin cancer who still spend a lot of time outdoors are the ideal candidates.</span></div> <div><span style="font-family: Calibri, sans-serif;"> </span></div> <div id="yui_3_16_0_1_1447968647113_116551"><strong><span style="font-family: Calibri, sans-serif;">In recognition of National Skin Cancer Action Week, here are four ways to be sun smart this summer:</span></strong></div> <div id="yui_3_16_0_1_1447968647113_116553"><span style="font-family: Calibri, sans-serif;"> </span></div> <div id="yui_3_16_0_1_1447968647113_116556"><span style="font-family: Calibri, sans-serif;">1.      Avoid outdoor activities during high UV periods during the middle of the day.</span></div> <div><span style="font-family: Calibri, sans-serif;">2.      Apply a broad-spectrum, high SPF sunscreen every day. Look for foundations or moisturisers that contain sunscreen to add to your routine.  </span></div> <div><span style="font-family: Calibri, sans-serif;">3.      Opt for a hat and sunglasses when possible. Time spent in the car is an often overlooked activity that involves sun exposure.</span></div> <div id="yui_3_16_0_1_1447968647113_116560"><span style="font-family: Calibri, sans-serif;">4.      Set reminders to have regular skin checks with your dermatologist or GP. Consult a medical professional if you believe you might benefit from a health supplement such as nicotinamide.   </span></div> <p><span style="font-family: Calibri, sans-serif;"><strong> </strong></span></p> </div>

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